Katie McCabe and her Arsenal team-mates will square up to holders Barcelona in the group stages of the new-look Women's Champions League.
The Gunners came through two qualifying rounds to reach the group stage having finished third in the WSL last season.
They will face Barca in Group C, where they were also paired with Hoffenheim and HB Koge.
The current Women's Super League champions Chelsea have also been handed a tough draw.
Emma Hayes' side lost last year's final to Barcelona in Gothenburg but were seeded in pot one for Monday's draw having won the WSL.
In the competition's first-ever group stage, the Blues were drawn in Group A with Juventus - who have won the last four Serie A titles and are managed by former Arsenal head coach Joe Montemurro.
They will also come up against DFB Pokal holders Wolfsburg, having beaten the German side in the quarter-finals last season, and Swiss champions Servette - who overcame Clare Shine's Glasgow City to reach this stage of the competition.
Despite the competition, Chelsea will still be favourites to progress as group winners, with the top two from each of the four groups qualifying for the quarter-final stage this year.
As well as a reformatted tournament, the Women's Champions League has a new television deal in place from the group stage onwards, with the matches streaming free on DAZN's YouTube channel.