With Peamount United away on UEFA Women's Champions League duty, Shelbourne took full advantage to move back level at the top of the table.
Emily Whelan put The Reds in front with a shot from distance that was too hot to handle before Alex Kavanagh converted a penalty - only minutes after Saoirse Noonan failed to score from the spot.
Leah Doyle, on her first start of the season, got in front of her marker to score their third goal from close range. Noonan then had another penalty saved by Abbiegayle Royanne but her persistence paid off when she scored on 88 minutes with a side-footed finish.
While manager Noel King will be pleased with the three points, the clean sheet and the performance, the return of Chloe Mustaki from injury after 18 months out was the day's most positive outcome.
The Gypsies were rampant in a rain-sodden Dalymount Park as they celebrated a record win in just their second season in the Women's National League.
There were so many impressive performances from Bohemians - none more so than midfielder Niamh Kenna - but credit deserves to be shared out as they clinched their fourth win of the campaign.
Lisa Murphy headed in the opener when meeting a corner and Erica Burke then bundled a ball over the line to make it 2-0 going in at the break. But they didn't ease up one bit as the rain poured down.
Abbie Brophy scored a half volley just before the hour mark, Chloe Darby rose highest to meet a corner kick with a firm header and youngster Lara Phibbs fired in a fifth from inside the penalty area.
Treaty midfielder Jenna Slattery won and converted a penalty as a consolation.
When Eva Mangan fired in a stunning long-range goal for Cork, there were a lot of concerned faces around Eamonn Deacy Park but Galway quickly recovered to seize control.
Chloe Singleton was alert at the back post to hook in the equaliser before Kate Slevin and Emma Starr got one apiece to give the home team a commanding lead at the interval.
Cork never found any rhythm to their play and Galway kept them under pressure with the experienced Lynsey McKey pulling the strings like a master puppeteer.
Substitute Aoife Thompson finished well inside the penalty area, Starr got her second with a shot that rebounded in off the goalkeeper and Ellie O'Flaherty smashed in the final goal just before the full-time whistle sounded.