Dundalk v Bohemians, Oriel Park, 5.45pm, live on WATCHLOI
Bohemians are the only side that can prevent Shamrock Rovers from winning the league and they face a tricky game away to Dundalk
A draw or defeat for Keith Long's side would mean a win for their Dublin rivals would be enough to end the title race.
They could seal second place in the league with victory, however.
The Lilywhites need points to secure European football next year. Last Tuesday's victory over Cork City put them in third place and they'll be trying to secure that position over the next five games.
Dundalk: Dane Massey continues his recovery from hip surgery and remains side-lined. Darragh Leahy has returned from international duty with the Ireland Under-21s and is available for selection. Massey is the only absentee
Bohemians: An unnamed first team player has tested positive for Covid-19 while another player, deemed to be a close contact will have to self-isolate until 20 October.
Bohs have made no request for tonight's to be rescheduled and say they "are happy that the fixture will proceed as planned."
What they said
Dundalk manager Filippo Giovagnoli: "We did some rotation after the Europa League matches. I know some people criticised our results that we had at home, but we had to rotate the players.
"The thing was to have all of them fit and sharp for us to be competitive.
"Every game we play from now is important - the league, the Europa League - there is a big prize. I'm not forgetting the FAI Cup at the end of November.
"We want to do well in every competition and I think now we are ready and prepared to do so."