Kai Havertz's hat-trick spearheaded Chelsea's 6-0 Carabao Cup hammering of Barnsley as Thiago Silva and Ben Chilwell enjoyed promising Blues debuts.
Germany playmaker Havertz bagged his first Chelsea goals, relishing a more central role as Frank Lampard's men overpowered their Championship opponents.
Tammy Abraham, Ross Barkley and Olivier Giroud also found the net in a dominant Chelsea display at Stamford Bridge.
Toni Rudiger's omission for Chelsea's squad for the second match in a row left the Germany defender eyeing a loan exit before the 5 October transfer deadline.
Silva's arrival could push Rudiger down the pecking order in west London, with the Brazil stalwart adding immediate organisation in an authoritative hour's work.
Fikayo Tomori's return to the first team fold could compound Rudiger's situation, and the 27-year-old could now seek a move during this window.
Ben Chilwell also made his Chelsea debut after his summer transfer from Leicester, setting up the sixth goal for Giroud.
Everton goalkeeper Jordan Pickford was left wishing he had been rested for the 5-2 win at League One side Fleetwood after two errors of judgement made for an awkward night.
The visitors were coasting at half-time through two Richarlison goals only for England's number one to blunder three minutes after the restart.
Pickford, one of five players retained from Saturday's victory over West Brom, dithered over a clearance virtually under his own crossbar and it was charged down to allow substitute Mark Duffy a free shot.
Alex Iwobi looked to have rescued his team-mate with a goal less than two minutes later only for more indecision from Pickford, who sat out the previous round last week to allow Joao Virginia to make his debut, to lead to another goal.
Having started to come for Glenn Whelan's far-post cross he changed his mind and when the ball was played back in, he got a hand to Callum Camps' overhead kick which was straight at him but could not keep it out.
For the second time in 10 minutes Ancelotti was left speechless and shaking his head in his technical area.
It made for an uncomfortable final half-hour even after Bernard fired home a fourth and substitute Moise Kean scored with Everton's last kick of the night.
Joelinton's brace helped Newcastle on their way to a 7-0 demolition of 10-man Morecambe.
Having been humbled at home to Brighton on Sunday, Steve Bruce's men emphatically booked a fourth-round trip to Newport as his much-changed side ran amok at the empty Mazuma Stadium.
Joelinton netted twice as Newcastle hit five in an opening period made all the more difficult for Morecambe by Toumani Diagouraga's red card, with the hosts digging deep to restrict the Premier League side to just two more after the break.
Miguel Almiron rounded the goalkeeper to add another, before Jacob Murphy curled home and the Magpies' Brazilian frontman scored a screamer from distance.
The League Two side saw Diagouraga sent off for a lunge on Sean Longstaff before Isaac Hayden smashed home in stoppage time as Newcastle scored five first-half goals in a match for the first time since 1993.
The second period was one of damage limitation for Derek Adams' Shrimps, who only conceded Jamaal Lascelles' header and a Sam Lavelle own goal despite the continuing one-way traffic.
Republic of Ireland youngster Troy Parrott made his Millwall debut but it was a thunderbolt from Josh Brownhill which sent opponents Burnley, who had Irish defender Jimmy Dunne in their ranks, on their way to a 2-0 victory in the Carabao Cup third round.
The wonder strike on the stroke of half-time, coupled with Matej Vydra's late effort, gave Sean Dyche a victory at his old club and means this is the joint-furthest the Clarets have gone in the competition since the 49-year-old took over in 2012.
Progress came at a cost with forward Jay Rodriguez injured early on, but it will be Burnley who host the Thursday night winner of Manchester City or Bournemouth at Turf Moor next week.
Brighton set up a fourth-round clash with Manchester United as they eased past Preston 2-0 at Deepdale.
Second-half goals from Alireza Jahanbakhsh and Alexis Mac Allister were enough for the Seagulls to advance, and they will now host Ole Gunnar Solskjaer's side next week.
Jahanbakhsh left Preston goalkeeper Connor Ripley with little chance when he rifled home a powerful shot just before the hour - and Mac Allister made sure when he thumped home from Pascal Gross' pull-back a little over quarter of an hour later.
Preston were left to rue a Patrick Bauer header which struck the crossbar in the first half but could have few complaints as Brighton finished the game the stronger of the two sides.
Bobby Decordova-Reid scored for the second successive match as Fulham eased to a 2-0 win over Sheffield Wednesday to set up a fourth-round tie with local rivals Brentford.
Reid, who was on target in Saturday's 4-3 loss at Leeds, slotted in Josh Onomah's centre to double the hosts' lead in the 32nd minute at Craven Cottage
Aboubakar Kamara had put the Premier League side on course for a relatively comfortable evening against lower-league opposition by turning home Anthony Knockaert's ninth-minute pass.
Scott Parker's side will make the short journey to the Brentford Community Stadium in the last 16, a repeat of last month's Sky Bet Championship play-off final.
Striker Tyrese Campbell's first goal of the new season helped Stoke beat Gillingham 1-0 to progress to the last 16 stage.
Campbell's clinical 37th-minute finish did the damage as the Championship side avoided an upset against their League One visitors and claimed their first home win of the season at the bet365 Stadium.
It was Campbell's first goal since the start of July when he bagged a brace in a 4-0 win over Barnsley, a result which helped Michael O'Neill's side retain their Championship status last season.
Victory was also Stoke's first home win over Gillingham for 16 years having last beat them 2-0 in their own backyard on 21 August 2004.
James McClean was among the starting side for Stoke as was Irish defender Nathan Collins.