Anthony Martial's first ever Manchester United hat-trick saw Ole Gunnar Solskjaer's side coast to a comfortable victory over fellow European hopefuls Sheffield United.
Having been roared to derby victory against Manchester City in their last home match, giant stadium wraps replaced supporters as an empty Old Trafford hosted competitive football for the first time in 108 days.
Manchester United dealt with the unusual backdrop superbly and secured their first victory since football resumed amid the coronavirus pandemic, with Martial's treble sealing a deserved 3-0 win against Sheffield United.
It was the hosts' first Premier League hat-trick since Robin Van Persie hit three in 2013, extending their unbeaten run to 13 matches and boosting their top-four hopes on a night that had initially been pencilled in for a neutral venue.
Chris Wilder had called this a clash between his Ford Fiesta and a Ferrari, so the Blades boss could have done without his defence, which had been shorn of the suspended Republic of Ireland international John Egan, stalling with seven minutes on the clock as Martial turned home Marcus Rashford's cross.
Paul Pogba put in a promising performance on his first start since September and there was a snapshot of what could lie ahead alongside Bruno Fernandes, with the pair involved before Martial met Aaron Wan-Bissaka's cross.
The France international moved onto 19 goals for the season - the best return of his career - by superbly scooping the ball over Simon Moore late on as the hosts secured a surprisingly routine win.
Rashford set up the opener as he drilled in for Martial to tuck in at the near post with just seven minutes on the clock.
It should have been two shortly afterwards. Having blocked a George Baldock shot, Solskjaer's side broke at speed and Rashford put Martial through.
The Frenchman turned the ball back to his team-mate after drawing the goalkeeper, but Rashford somehow scuffed his attempt wide under pressure.
Martial would put United clear just before the break. Fernandes and Pogba coolly moved the ball onto Wan-Bissaka, who impressively turned Ireland defender Enda Stevens and crossed for the France forward to sweep home at the near post.
Martial wrapped up his hat-trick in the 74th minute, showing wonderful composure to scoop the ball over Moore after playing a one-two with Rashford.
Solskjaer took off the hat-trick hero as the Manchester United boss made five substitutions in one fell swoop with the encounter over as a contest.