Paul Pogba's recovery from an ankle injury has been compounded by illness, with Ole Gunnar Solskjaer suggesting it has set the Manchester United midfielder "back quite a bit".
Having fuelled speculation about his future during a summer of intense scrutiny, the 26-year-old has not featured since September due to an ankle injury that has restricted him to just six appearances this season.
United manager Solskjaer has spoken confidently about the Real Madrid target returning to action before the end of the year and Pogba had been due to resume first-team training this week, only to succumb to a new problem.
"Of all things he's struck down ill now," Solskjaer said on Sunday, when previewing the Carabao Cup quarter-final against Colchester.
"He's been off for two or three days - three days probably - so that's not beneficial. That's probably set him back quite a bit."
Solskjaer's comments came just hours before videos were posted on social media on Sunday evening, with Pogba dancing and showing few ill effects at his brother Florentin's wedding.
The midfielder had permission to attend the wedding in France on Friday, before falling ill on Saturday and getting worse on Sunday.
"As I've said so many times, Paul's a top, top player that we want to see playing his best football at Man United," Solskjaer said.
"We just need to get him fit and match fit. It might be half an hour, 45, 60, 90 - who knows, the first game. We're working hard to get him back but now he's ill."
Pogba's presence was certainly missed on Sunday, when United were crying out for a creative midfielder in the 1-1 league draw with Everton.
"We can talk about Paul all day long and it's games like this for example when you're lacking that one creative pass or ideas maybe," Solskjaer said.
"He has that quality that not many midfielders in the world have so to get him back would be great."
Pogba will again be sidelined as United take to the field on Wednesday, when Diogo Dalot could make his first appearance in 10 weeks.
Marcos Rojo, Timothy Fosu-Mensah and Eric Bailly remain sidelined as United look to progress past League Two side Colchester and reach the Carabao Cup semi-finals.
"Any player or any team - and for us now it's a good team that's building - would benefit a lot from winning a trophy or getting to a final, of course winning it is major," Solskjaer said.
"Now we've got a chance of getting into the semis so for us this game is a big one."