Ireland will be without the services of Derrick Williams for their must-win European Championship qualifier with Denmark at the Aviva Stadium on Monday evening.
Williams has returned to his club Blackburn Rovers for treatment on a calf strain picked up during Thursday night's 3-1 win over New Zealand in Dublin.
Ireland manager Mick McCarthy told FAI.ie: "Derrick felt his calf in the second half of the game and our medical team have assessed him today.
"He will go back to his club now and we wish him well. He was one of our best players on Thursday night and deserved his goal."
McCarthy has no plans to add to his 25-man squad ahead of Monday's sell-out game at the Aviva.
Debutant Lee O’Connor has returned to the Ireland Under-21 squad ahead of their Euro qualifier against Sweden in Tallaght on Tuesday, 19 November.
"Lee had a really good debut, I was impressed with him and I’ve told him to be very proud of how he played," added McCarthy.
Troy Parrott remains in McCarthy's squad and could be in line to play some part in Monday's clash in Dublin.
The Ireland players who didn’t feature against New Zealand trained at the FAI National Training Centre on Friday afternoon while those who did play underwent a recovery session.
The Ireland squad are due to watch Denmark’s Group D clash against Gibraltar after dinner on Friday night.