There will be no repeat of Burton's fairytale run to the semi-finals of the Carabao Cup this season after Leicester eventually proved too strong at the Pirelli Stadium.
The League One side claimed famous victories against Aston Villa, Burnley, Nottingham Forest and Middlesbrough en route to the last four of the competition during the 2018/19 campaign, but there was to be no more giant-killing on Tuesday night.
Burton, who added Bournemouth to their growing list of scalps in the previous round, did pull a goal back through Liam Boyce early in the second half after strikes from Kelechi Iheanacho and Youri Tielemans had given Leicester a two-goal cushion at half-time.
Brendan Rodgers' team were put under some intense pressure in the second half but survived several difficult spells and sealed a place in the quarter-finals for the third year in a row when substitute James Maddison struck in the final minute.
Sunderland's Will Grigg and Marc McNulty both failed to convert from the spot as Oxford won 4-2 on penalties after a 1-1 draw at the Kassam Stadium.
Oxford, who dumped West Ham out after winning 4-0 in the previous round, led at the break through Rob Hall's effort before McNulty equalised for Sunderland with 12 minutes left.
James Henry, Anthony Forde, Tariqe Fosu-Henry and John Mousinho all converted in the shoot-out for Oxford, while Grigg blazed his spot kick off target and McNulty's effort was saved.
Colchester extended their run into the latter stages of the competition with a 3-1 win at Sky Bet League Two rivals Crawley.
Dannie Bulman's curling first-half finish for Crawley was cancelled out two minutes later by Luke Norris's header.
Michael Luyambula's own goal early in the second half gave Colchester the lead and Luke Gambin added their third.
