James McCarthy has pulled out of the Republic of Ireland squad for the upcoming Euro 2020 qualifier with Switzerland to focus on regaining full fitness at his club Crystal Palace.
Luton Town striker James Collins, Fulham defender Cyrus Christie and Burton Albion goalkeeper Kieran O'Hara have been called into the Republic of Ireland squad for the Swiss clash and the following friendly with Bulgaria.
The trio replace the injured Sean Maguire (eye), Matt Doherty (knee) and Keiren Westwood (knee) for the Dublin double-header at the Aviva Stadium.
Manager Mick McCarthy said he spoke with his namesake James and they came to the decision.
"I have spoken at length to James [McCarthy]. He has recently moved to Crystal Palace and is only back playing," said Ireland manager McCarthy.
"James is completely free of injury but the intensity of the Switzerland game was always going to be too much for James and we discussed that. Like James, Keiren Westwood will work away now at his club and we will see how they are before we go to Georgia and Switzerland next month."
Preston North End striker Maguire suffered a freak injury when he was struck in the face by a ball at training last week and missed Saturday's draw at Nottingham Forest, while Doherty was left out of the squad for Wolverhampton Wanderers' visit to Everton on Sunday with a knee injury.
"It is hard on the four players to miss out for a game as big as the Switzerland match," added manager McCarthy.
"We have a 24-strong squad now with James, Cyrus and Kieran coming in and we will get to work on Monday."
The Ireland squad assembled at the team base in Dublin on Sunday afternoon and will train on Monday.