Ajax survived a late sending-off to secure a 0-0 draw in their Champions League play-off first leg away clash against APOEL.
Noussair Mazraoui was dismissed after receiving a second yellow card 10 minutes from time, but last season's Champions League semi-finalists held on.
Cluj, conquerors of Celtic in the previous round, have it all to do after suffering a 1-0 home defeat against Slavia Prague.
Lukas Masopust's goal after 28 minutes stung Cluj, and they could find no way back into the contest.
Club Brugge are also in the box seat following a 1-0 success against LASK Linz in Austria.
The Belgian side struck early through Hans Vanaken's penalty and they did not look back as they target a place in the competition proper.