Jose Antonio Reyes, the ex-Arsenal and Spain forward, has died in a car crash at the age of 35, former club Sevilla have announced.
Reyes was part of Arsenal's 'invincibles' squad that won the 2004 Premier League title without suffering defeat.
He also played for Real Madrid, Atletico Madrid and Benfica during his career, as well as winning 21 caps for Spain.
Sevilla said in a statement on Twitter: "We couldn't be confirming worse news. Beloved Sevilla star Jose Antonio Reyes has died in a traffic collision. Rest in peace."
We couldn't be confirming worse news. Beloved Sevilla star José Antonio Reyes has died in a traffic collision. Rest in peace. pic.twitter.com/qeGl2nsi3c— Sevilla FC (@SevillaFC_ENG) June 1, 2019
Reyes started his career at local club Sevilla and returned to the Andalusian side in 2012, helping them to win three successive Europa League titles.
He left the club in 2016 and played for Espanyol, Cordoba and Chinese side Xinjiang Tianshan Leopard before returning to Spain to join Extremadura earlier this year.
The second division club said in a statement on their Twitter account: "With a broken heart Extremadura UD announce the death of their player Jose Antonio Reyes in a traffic accident."
Reyes' former Arsenal team-mates Thierry Henry and Ray Parlour took to Twitter to express their condolences.
Henry tweeted: "I'm devastated to hear the sad news about Jose Antonio Reyes. Wonderful player, superb team mate and exceptional human being. I wish his family and friends continued strength and courage to get through this difficult time. #takenfartoosoon."
Parlour added: "So Sad team mate of mine and great talent RIP Jose."
Real Madrid captain Sergio Ramos, who like Reyes came up through the youth ranks at Sevilla and was a team-mate of his with Spain and Real, tweeted his shock at the death of his friend.
The 33-year-old wrote in Spanish: "Broken. Destroyed. I have no words. All the love to the family. We'll always remember you, friend! RIP brother."
Scores of clubs across Spain and Europe also tweeted their condolences, including Barcelona who wrote: "FC Barcelona wishes to express their deepest condolences for the death of footballer Jose Antonio Reyes, a brilliant and charismatic player; one of the most outstanding figures and with a great trajectory in football. Rest in peace."
Portuguese giants Benfica, where Reyes played on loan for the 2008/09 season, added: "We're devastated to hear of the passing of our former player Jose Antonio Reyes. Our thoughts are with his family and friends. Rest in peace, Jose."