Brighton overcame the dismissal of Republic of Ireland defender Shane Duffy to beat rivals Crystal Palace 3-1 at the Amex Stadium.
The Seagulls went in front after 24 minutes when former Palace frontman Glenn Murray converted a penalty, in off the crossbar.
However, Brighton were soon down to 10 men when Duffy was shown a straight red card for pushing his head into the face of Patrick van Aanholt as they squared up.
The hosts, though, doubled their lead on the half-hour when substitute Leon Balogun smashed the ball in at the back post from a corner just 25 seconds after coming on.
Brighton wrapped things up on the stroke of half-time when Florin Andone, who had earlier replaced the injured Murray, produced a determined run and angled finish.
Palace scored a late consolation through a penalty from Luka Milivojevic.
Lucas Perez scored his first Premier League goals for West Ham to fire them to a 3-1 victory over Cardiff.
The summer signing from Arsenal, on as a substitute for the injured Marko Arnautovic, found the net twice as the Hammers recorded back-to-back top-flight wins for the first time in almost two years.
Cardiff, still without an away win this season, blew a golden chance to take the lead when Joe Ralls missed a first-half penalty.
And Perez punished them after the break with a quickfire double before Michail Antonio also opened his Premier League account for the season.
A blistering start by Bournemouth saw them end their four-game league losing streak with a 2-1 win over Huddersfield at the Vitality Stadium.
The Cherries had lost to Newcastle, Manchester United, Arsenal and Manchester City in recent weeks but goals in the opening 22 minutes from Callum Wilson and Ryan Fraser got them back on track.
They did have to battle for the three points after that, though, as the Terriers came back strongly and made a game of it through Terence Kongolo's header shortly before the break.
David Wagner's men pushed for a leveller in the second half, but lacked a cutting edge, despite having 21 shots on goal, and slipped to a ninth defeat of the season.