Shane Duffy was, once again, on the scoresheet as Brighton beat Huddersfield 2-1 at John Smith's Stadium.
Mathias Jorgensen opened the scoring for the home side in the first minute, but Brighton fought back to secure their first ever, come-from-behind Premier League victory.
Steve Mounie was given his marching orders after 32 minutes and Duffy levelled on the stroke of half-time before Florin Andone bagged the winner midway through the second half.
Newcastle's three-match winning run was abruptly halted as a goal in either half from Javier Hernandez and Felipe Anderson's injury-time strike gave West Ham a comprehensive 3-0 win at St James' Park.
Burnley crashed to a fifth defeat in their last six matches and remain in the bottom three after Crystal Palace prevailed 2-0 at Selhurst Park.
The Eagles were only ahead of Burnley in the table on goal difference at the start of the day, but they stole a march when James McArthur's cross drifted into the net in the 16th minute.
Andros Townsend made sure of the win when he cut in from the right and unleashed a fine drive with his left foot from just outside the area that flew past helpless Burnley goalkeeper Joe Hart.
Leicester moved above Watford and up to seventh after a 2-0 victory at the King Power Stadium.
Jamie Vardy netted a 12th-minute penalty after being fouled in the area by Hornets goalkeeper Ben Foster and James Maddison doubled their lead midway through the first half.
Watford's miserable afternoon was compounded in the closing stages when Etienne Capoue was given a straight red card after an apparent two-footed challenge on Kelechi Iheanacho.
