French investigators are probing suspicions of match-fixing in Paris Saint-Germain's 6-1 win against Red Star Belgrade in the Champions League group stage on 3 October.
A senior official from the Serbian club is suspected to have bet large sums of money on Red Star losing by a five-goal margin, according to a report from French sports newspaper L'Equipe.
The match was played at PSG's Parc des Princes stadium.
L'Equipe said the Red Star official and accomplices had bet €5million on the match with the aim of winning tens of millions of euros.
The original alert tip-off was received by UEFA which passed on the information to national authorities, another source said.
France's online betting watchdog Arjel said it had seen no evidence of irregular activity regarding the match either in France or in 22 other mainly European countries, or by countries covered by the Global Lottery Monitoring System.
A Red Star Belgrade spokesman, Nebojsa Todorovic, told AFP: "I cannot comment on this in any way."
PSG said it was "extremely concerned" by the investigation.
In a statement, the French club said its contact with Red Star for the match had been completely normal.
"At no moment was any member of the club approached about any issue other than those strictly linked to the organisation of the match, for example meetings, visits and the official lunch just as there is for every UEFA Champions League match," PSG said.
UEFA said it did not comment on ongoing investigations.
Neymar scored a hat-trick in the match with PSG's other goals coming from Edinson Cavani, Angel Di Maria and Kylian Mbappe.
Marko Marin scored Red Star's only goal.