Jon Walters has been ruled out until Christmas after manager Martin O’Neill confirmed he would have "no chance" of making the World Cup qualifying play-off.
The Burnley striker has been absent since 24 August due to a knee injury and took a watching brief as James McClean fired Ireland into a clash with either Italy, Croatia, Denmark or Switzerland next month.
Sky Sports News are reporting Walters will miss at least two more months as he recovers from the knee problem.
Seamus Coleman is unlikely to be available as he makes the final stages of his rehabilitation from a broken leg, while David Meyler is suspended.
Robbie Brady face a nervy wait on his availability as an alleged headbutt is being accessed by FIFA.
However, it is understood the Ireland camp is relaxed over the matter.