Wales midfielder Joe Allen looks likely to miss Sunday's Group D World Cup qualifying match against Georgia with a hamstring injury.
Allen, who scored Wales' opening goal in Thursday's 2-2 draw with Austria, was withdrawn early in the second half due to the injury.
Wales, who top the Republic of Ireland's Group D on goal diffrence after two games, will also be without injured midfielder Aaron Ramsey at the Cardiff City Stadium.
"We probably could have gambled and kept him on the pitch but we don't want to being doing that. He had a twinge in his hamstring, so that's why we took him off immediately," Coleman told reporters.
Coleman's side beat Moldova 4-0 last month, with that goal rush enough to edge them ahead of Serbia, Austria and Ireland, who all have four points in the bag.