Chelsea (4) v Burnley (8), 3pm
Chelsea midfielder Willian will have a fitness test on a calf injury. Defender Kurt Zouma remains sidelined with a knee problem, while boss Antonio Conte also has another injury worry, but would not name the player concerned.
Burnley look set to recall captain Tom Heaton, record signing Steven Defour and striker Andre Gray. Neither forward Ashley Barnes (hamstring) nor Liverpool loanee Jon Flanagan are ready to feature, though.
Crystal Palace (19) v AFC Bournemouth (20), 3pm
Goalkeeper Wayne Hennessey and midfielder Joe Ledley are injury doubts for Palace, so Steve Mandanda could make his Premier League debut between the posts. Christian Benteke remains short of match fitness and will probably start on the bench.
Bournemouth have no fresh injury concerns, with Ireland international Harry Arter back in the squad after serving a one-match suspension.
Everton (5) v Stoke (17), 3pm
Everton will without Seamus Coleman, who is still recovering from an ankle injury. Ashley Williams and Yannick Bolasie should get first league starts, but James McCarthy, Tom Cleverley and Darron Gibson all have minor knocks.
Stoke winger Xherdan Shaqiri could return for Stoke after missing the last two games with a calf injury. But goalkeeper Jack Butland (ankle) and defender Glen Johnson (thigh) are still not fit, meaning Peter Crouch could keep his place.
Hull (3) v Man Utd (2), 5.30pm
Hull defender Harry Maguire is in contention for his first league appearance of the season following an ankle problem, while midfielder Jake Livermore could start in central defence alongside Curtis Davies.
Manchester United boss Jose Mourinho looks set to have a full squad to choose from. Jesse Lingard has missed the last two games, but has returned to training.
Leicester (15) v Swansea (12), 3pm
Nampalys Mendy is out for Leicester after suffering an ankle injury against Arsenal, meaning Andy King is set to start. Jeff Schlupp is a doubt with a muscle injury.
Neil Taylor will be missing for the Swans as he has opted to play in an under-23 fixture on Friday night to build fitness. Record signing Borja Baston remains out with a thigh injury, while Scotland Under-21 striker Oliver McBurnie has been added to the squad.
Southampton (16) v Sunderland (18), 3pm
Ryan Bertrand is poised for his first competitive Southampton appearance under new boss Claude Puel after recovering from knee trouble. Oriol Romeu has shaken off the knock he suffered in the 2-0 defeat at Manchester United, but Jeremy Pied is out.
Sunderland goalkeeper Jordan Pickford is in line to start, with Vito Mannone ruled out with damaged elbow ligaments. John O'Shea (hip), Lamine Kone (back), Fabio Borini (toe) and Jeremain Lens (foot) are being assessed and Javier Manquillo could feature for the first time. Jan Kirchhoff, Billy Jones, Lee Cattermole and Sebastian Larsson remain out.
Tottenham Hotspur (7) v Liverpool (11), 12.30pm
Dele Alli could return to the Tottenham side after an illness. Captain Hugo Lloris (hamstring) is still out, so Michel Vorm will again deputise in goal, while Mousa Dembele is suspended.
Liverpool's Philippe Coutinho is a doubt with a minor hamstring issue. Emre Can is a doubt with an ankle problem, while striker Divock Origi will be assessed. But defender Joel Matip is pushing for his first league start.
Watford (14) v Arsenal (13), 3pm
Watford's new signings Daryl Janmaat, Younes Kaboul and Roberto Pereyra are unlikely to start, with manager Walter Mazzarri is not expected to ring the changes.
Mesut Ozil could be set for his first start of the season for Arsenal, but Olivier Giroud is unlikely to be recalled. Aaron Ramsey (hamstring), Alex Iwobi (thigh), Per Mertesacker, Danny Welbeck and Carl Jenkinson (all knee) are still missing.
SUNDAY
West Brom (9) v Middlesbrough (6) 1.30pm
West Brom defender Kane Wilson could become the first player born in the 21st century to feature in the Premier League, with Brendan Galloway doubtful because of a hamstring injury. Chris Brunt is still out with a knee problem.
Middlesbrough are without a specialist left-back, with George Friend (calf), Fabio da Silva (knee) and James Husband (dislocated shoulder) all out. Goalkeeper Victor Valdes and midfielder Marten de Roon (both hamstring) are also out, but defender Bernardo Espinosa is fit.
Man City (1) v West Ham (10), 4pm
New Manchester City goalkeeper Claudio Bravo will not go straight into the team, meaning Willy Caballero is expected to start again ahead of Joe Hart. Striker Kelechi Iheanacho has been cleared of serious injury, but captain Vincent Kompany, right-back Bacary Sagna and midfielders Leroy Sane and Ilkay Gundogan are not yet fit.
We need your consent to load this rte-player contentWe use rte-player to manage extra content that can set cookies on your device and collect data about your activity. Please review their details and accept them to load the content.Manage Preferences
Dimitri Payet and Manuel Lanzini could return from injury and skipper Mark Noble has shaken off a knock, but Havard Nordtveit has joined Andy Carroll, Andre Ayew, Aaron Cresswell, Sofiane Feghouli and Diafra Sakho on the sidelines.
The Hammers hope to sign Simone Zaza before the weekend.