Irish Daily Mail FAI Cup holders Dundalk will face seven-time winners Shelbourne in the second round of this year’s competition.
Elsewhere, Shamrock Rovers - the most successful team in the history of the competition - will face minnows Midleton as part of a packed first day of a thrilling FAI Cup weekend.
The first games will kick off next Friday, while further matches will follow on Saturday and Sunday.
If any fixtures go to replays, there will be a quick turnaround, with many of the potential ties scheduled for the following week.
Irish Daily Mail FAI Senior Cup
Friday, 20 May
Bohemians v Galway United, Dalymount Park, 19:45
Cork City v St Peter's, Turner's Cross, 19:45
Derry City v Drogheda United, Brandywell Stadium, 19:45
Dundalk v Shelbourne, Oriel Park, 19:45
Firhouse Clover v Wexford Youths, Ferrycarrig Park, 20:00
Shamrock Rovers v Midleton, Tallaght Stadium, 20:00
UCD v Bray Wanderers, UCD Bowl, 19:45
Waterford United v Longford Town, RSC, 19:45
Saturday, 21 May
Athlone Town v Letterkenny Rovers, Athlone Town Stadium, 19:45
Bluebell United v Limerick, Markets Field, 14:00
Cobh Ramblers v Cherry Orchard, St Colman's Park, 14:30
Finn Harps v Crumlin United, Finn Park, 20:00
Ringmahon Rangers v Glebe North, Ringmahon Park, 14:00
Sligo Rovers v Cabinteely, The Showgrounds, 19:45
St Patrick's Athletic v Pike Rovers, Richmond Park, 15:00
Sunday, 22 May
Janesboro v Sheriff YC, Pearse Stadium, 14:00