Bohemians v Cork City, 7.45pm
Bohemians manager Keith Long says his players won't need any picking up as they bid to end their barren run.
Friday's 0-0 draw away to Finn Harps made it five league games without a win or goal.
Bohs spurned a golden opportunity to bring that run to an end when Anto Murphy saw his injury-time penalty saved by Harps goalkeeper Ciaran Gallagher.
After a sluggish first series of fixtures, the Gypsies sit ninth with 11 points from 11 games.
But Long is adamant his players won't need any extra motivation when taking on second-placed Cork City and said: "They're professionals - the lads won't need picking up.
"I saw Cork against Bray Wanderers on Saturday. They were very comfortable once they got the first goal and gave a professional performance to see the game out 2-0. They've quality players in every position.
"We played them on the opening day of the season and, after matching them for 60 minutes, two defensive mistakes cost us. But this will be a different game and we will be up for it."
Bohs are once again without Ismahil Akinade (hamstring), Jason Caffrey (hamstring) and Adam Evans (virus) but James Kavanagh (virus) is back in contention.
Ayman Ben Mohamed, who came off with a groin strain at half-time against Harps, is a doubt.
City go into the game on back of four consecutive league wins, with their last outing seeing them record a 2-0 win away to Bray Wanderers on Saturday. That win sees them sitting second in the table.
“It’s our best start to the season since we came in as a management team, so we are just hoping that we get the confidence from that and that the lads believe in themselves," said John Caulfield.
"They can see that there are goals in the team and they have shown that they can create chances.”
John Kavanagh, Eoghan O’Connell, Gearóid Morrissey, Alan Bennett are unavailable through injury.
Dundalk v Bray Wanderers, 7.45pm
Dundalk's 2-1 win over Galway United at Oriel Park on Friday and other results ensured that the Louth side retain their four-point lead at the top of the table.
This is the second meeting between the sides this season having already met on the opening weekend where Dundalk were 3-1 winners at the Carlisle Grounds.
The Lilywhites have only lost one of the last 13 to the Wicklow side.
Striker David McMillan said: “The games are really coming at us, it’s good to have three games in a week.
"You want to play as many games as possible. Bray have had a change of form since they had a change of management and we had a very difficult game there earlier in the season but we are looking forward to it."
Dundalk are without long-term striking duo Ciarán Kilduff (broken back) and Ciarán O’Connor (broken metatarsal), while Ciaran’s brother Michael missed Friday evening’s win with ankle ligament damage and is likely to miss a few weeks.
Patrick McEleney is nearing a return from a hamstring injury but tonight’s game is likely to be too soon and captain Stephen O’Donnell (ankle) may be available next week.
Bray come in off the back of a 2-0 defeats to Cork and Shamrock Rovers and occupy tenth place in the table.
Team news to follow if available.
Galway United v St Patrick's Athletic, 7.45pm
The Tribesmen remain unbeaten at Eamonn Deacy Park and they will look to continue that run against the Saints.
When the sides last met on opening day, United were 3-1 winners at Richmond Park and currently only two points separate the sides as they look to stay in touch with the top four.
"We're always looking to get three points at home," manager Tommy Dunne said.
"St Pats probably haven't had the results that they would've liked so far, but in saying that, they've done quite well.
"They've beaten Rovers and Bohemians. They have shown that they can pick up big results. They're a good technical team."
United's influential captain Ryan Connolly could miss three or four weeks of action with a calf tear, while Stephen Folan (back injury) and Padraic Cunningham (knee) are also unavailable for selection.
The Saints will be hoping to bounce back from last Friday's 1-0 home defeat to Derry City.
The Inchicore side remain without top-scorer Christy Fagan through injury, while youngsters Jack Bayly and Conor O'Malley remain out with thigh and ankle injuries respectively.
"Galway have had a good start to the season and Tommy Dunne has his side playing well," Athletic manager Liam Buckley told stpatsfc.com.
"They have had a great first series of games this year and will be looking to continue that.
"We know better than any team how good they can be judging by their second half display in Richmond Park a few months ago so it'll be a tough game."
Derry City v Finn Harps, 8pm
Derry looked out of sorts in the first meeting of the sides at Finn Park, a 2-1 loss, but they have gone on to lose only once in their next ten games and have taken 23 points out of a possible 30 since.
Their last outing was a 1-0 win against St Pat's.
Harps, for their part, have also started the season well and picked up their 12th point of the season on Friday night after a scoreless draw with Bohs at Finn Park.
Although not quite in the form of their near neighbours, nobody at Finn Park will be complaining too much about how they have started the campaign.
“Derry are third in the table for a reason and have been in excellent form,” said Harps boss Ollie Horgan.
“It could be a long evening for us especially with the quality that Derry have in their squad. It will be hugely difficult to get a result in there but we’ll prepare as best as we can and see where that takes us.”
Josh Mailey (groin), Raymond Foy (hamstring), Michael Rafter (ankle), Matthew Crossan (knee), Gareth Harkin (calf), Keith Cowan (foot) are all in the injury list.
Longford Town v Wexford Youths, 8pm
Longford haven't won a Premier Division match since that opening day win against Wexford, while Youths single victory against Bray Wanderers seems like an eternity ago also.
Rhys Gorman is unavailable through injury.
Wexford manager Shane Keegan will be looking for his team to learn quickly from their mistakes and take their chances against the teams around them in the top flight.
He said: "We were very disappointed not to take any points from the Longford game in our own place.
"We played well and had the vast majority of the possession but they defended very well and made it hard for us to break them down.
"We're not happy with our points total from the first round, simple as that. But there's no magic wand, its simply a case of working harder than ever before and if we all do that it will turn around, I have no doubt about that."
On the injury front, Youths continue to be without Lee Grace, Aidan Keenan and Peter Higgins with Shane Dunne back pushing for his first start of the season.
Shamrock Rovers v Sligo Rovers, 8pm
Shamrock Rovers are coming into this one after a 2-0 win over Longford Town on Saturday evening and currently sit in fourth, seven points behind pacesetters Dundalk.
For the match itself, the Hoops are without Luke Byrne, who’s been ruled out for the remainder of the season, while David O'Connor and Trevor Clarke are unavailable; Max Blanchard is doubtful.
The Bit o’Red go into the game on the best run of form for two years with three wins in a row, the most recent of which was a 4-1 win against Wexford Youths.
When the teams met earlier in the season for Dave Robertson’s first game in charge, the Hoops took a 2-0 win.
The Connacht side's boss is happy with the team’s recent form but is putting all the focus on getting a good result.
He said: “Once we are in good form we want the games to continue coming.
"They are coming thick and fast and the moment and that’s a good thing for us, they can’t really come quick enough.
"The lads had a very good weekend and have done well in the recovery session and in training today. We are just fully focused now on the next game which is Shamrock Rovers.
Tim Clancy is still a slight doubt for the visitors.