Robbie Keane scored twice but the Irishman's efforts were in vain as the Los Angeles Galaxy were dealt a 5-2 shock defeat by the Portland Timbers in the MLS.
Keane opened the scoring and gave Galaxy a 1-0 half-time lead with a beautifully placed lobbed volley before Portland stormed back and scored five times in the second half, three of which were inside a 10 minute spell.
Oh, Robbie Keane... what can't you do? #LAvPOR http://t.co/Jrhg1cRNRh— Major League Soccer (@MLS) October 19, 2015
The Irish captain's second goal did give LA hope as his clever header found the net to pull the score back to 3-2 but that rally proved to be short lived.
Portland's fourth goal, by Liberian midfielder Darlington Nagbe, came just 18 seconds after play had restarted following a second Keane goal.
The Galaxy would have secured a semi-final spot in the Western Conference semi-finals with a game to spare had they won.
The win lifted the Timbers to fourth in the West with 50 points, two points clear of the Seattle Sounders and Sporting Kansas City, and three in front of seventh-placed San Jose Earthquakes.
The top six teams in each conference advance to the post-season.
Seattle secured a 1-1 away draw against the Houston Dynamo.
Mike Grella scored the fastest goal in MLS history when his strike after seven seconds set the New York Red Bulls on their way to a 4-1 win over the Philadelphia Union
New York secured top seeding for the Eastern Conference play-offs with their victory, which was never in doubt. Bradley Wright-Phillips doubled the home team's lead after four minutes, Grella scored his second and Kemar Lawrence made it a first-half rout when putting New York 4-0 ahead just before the break.
Sebastien Le Toux scored a 55th-minute consolation for Philadelphia.
Former Leeds midfielder Grella's landmark goal came from the Union's kick-off.
Cristian Maidana laid the ball back to team-mate Michael Lahoud who failed to read his intentions, and Grella reached it first, sprinting at goal before his left-footed shot took a deflection off defender Steven Vitoria and nestled in the bottom left corner.
The goal beat Tim Cahill's eight-second goal for the Red Bulls against the Houston Dynamo in October 2013.