Tottenham Hotspur striker Jermain Defoe is a major doubt for the St Stephen's Day visit of Aston Villa to White Hart Lane.
The England frontman suffered a knee injury during the warm-up before Saturday's 3-1 Barclays Premiership defeat at Newcastle and is unlikely to figure on Tuesday.
Aaron Lennon also missed out at St James' Park, while Robbie Keane (knee) and Jermaine Jenas (ankle) are long-term absentees.
Aston Villa boss Martin O'Neill will assess the fitness of key midfielder Gavin McCann before choosing his side.
McCann passed a late fitness on a hamstring problem to enable him to play against Manchester United but was substituted in the second half as a precaution.
Juan Pablo Angel or Milan Baros are likely to earn a recall up front as two games in the space of 72 hours could prove beyond Chris Sutton who still looks short of full match fitness.
Villa will be looking to end a run of seven games without a win which has damaged their hopes of claiming a European spot.
Tottenham squad: Robinson, Cerny, Chimbonda, Lee, Dawson, King, Assou-Ekotto, Stalteri, Davenport, Gardner, Zokora, Davids, Tainio, Murphy, Ghaly, Malbranque, Ziegler, Huddlestone, Berbatov, Mido, Defoe.
Aston Villa squad: Kiraly, Hughes, Mellberg, Cahill, Barry, Petrov, Davis, Gardner, McCann, Sutton, Agbonlahor, Olejnik, Angel, Baros, Bouma, Ridgewell, Samuel, Whittingham, Agathe.
