Holders Liverpool have been drawn against more eastern European opposition in the third qualifying round of the Champions League.
If they finish off FK Kaunas in next week's second leg at Anfield they face a trip to Albania or Bulgaria.
The Reds lead their Lithuanian opponents 3-1 after the first leg and will play KF Tirana or CSKA Sofia if they progress.
It is another long trip abroad for their fans but at least they avoided a Merseyside derby against Everton, who face Villarreal.
Reds chief executive Rick Parry admitted he was relieved to have avoided Everton. He said: "Clearly when you are not given country protection the conspiracy theorists assume what is going to happen, I don't think either club would have relished it."
Villarreal will present a formidable test for David Moyes' Everton team. They finished third in Spain's Primera Liga last season.
Everton chairman Bill Kenwright said: "It's just lovely to be here in the draw. Twenty years ago we would have been here by right, year in year out, and then Heysel happened.
"So to come back here there is a part of you that feels we should be here anyway and another part that has to say it's a miracle from miracle manager."
Manchester United are expected to face Debrecen as the Hungarians lead Hajduk Split of Croatia 3-0 after their second round, first leg.
But United secretary Ken Ramsden said: "It could be either club. We don't take anything for granted but it's a real step into the unknown - there's so much uncertainty.
"We really wanted Shelbourne but that was unlikely."
Ramsden admitted the Old Trafford club - who were also drawn to play at home first - are desperate to emulate their Champions League triumph of 1999.
He said: "For a club of our standing and history to win the competition twice is not what we perceive as acceptable."
Scottish champions Rangers face Trabzonspor of Turkey or Anorthosis Famagusta of Cyprus. The latter team lead 3-1 after the first leg.
Celtic would meet Serbian outfit Partisan Belgrade or Sheriff Tiraspol of Moldova if they were to pull off an unlikely comeback against Artmedia Bratislava, who they trail 5-0 from the first leg.
The first legs of the third round will take place on August 9 or 10, with the return matches on 23/24.
UEFA Champions League third round draw:
Basle 1893 v Werder Bremen
CELTIC or Artmedia Bratislava v Partizan Belgrade or FC Sheriff
Shakhtar Donetsk v Inter Milan
SHELBOURNE or Steaua Bucharest v Rosenborg
MANCHESTER UNITED v Debrecen or Hajduk Split
Malmo or Maccabi Haifa v Dynamo Kiev or FC Thun
EVERTON v Villarreal
LIVERPOOL or Kaunas v CSKA Sofia or Dinamo Tirana
Sporting Lisbon v Udinese
Valerenga or FC Haka v Clube Brugge
Rapid Vienna or F91 Dudelange v Rabotnicki or Lokomotiv Moscow
Anderlecht or Neftchi v Slavia Prague
Trabzonspor or Anorthosis v RANGERS
Brondby or Dynamo Tbilisi v Ajax
Real Betis v Monaco
Wisla Krakow v Panathinaikos
First leg: 9/10 August
Second Leg: 23/24 August
