It's the last round of the BKT United Rugby Championship before attention fully turns to the Guinness Six Nations with all four Irish provinces in action.
Munster are first up as they visit Glasgow to take on Franco Smith's table-toppers on Friday night.
Connacht have a mid-afternoon kick-off at Zebre Parma on Saturday, while champions Leinster welcome Edinburgh to the Aviva Stadium later.
Ulster host Cardiff at the Affidea Stadium to round off the weekend's action on Saturday evening.
TV
Glasgow v Munster (Friday, 7.45pm) and Zebre v Connacht (Saturday 3pm Irish time) are live on TG4 and Premier Sports, while Leinster v Edinburgh (Saturday, 5.30pm) and Ulster v Cardiff (Saturday 7.45pm) and all other games are available on Premier Sports and URC.tv.
ONLINE
We'll have live score updates, reports and reaction on rte.ie/sport.
WEATHER
Glasgow is set for thick cloud in a moderate breeze but the rain should hold off for Munster's match. Temperature of around 1C.
There are similar enough conditions forecast in Parma on Saturday afternoon for Connacht but the temperature is a little higher at 7C.
Dublin is expecting light cloud and light wind in 7C for Leinster's late afternoon kick-off, while Belfast looks like it won't escape the rain and wind on Saturday evening with temperatures a couple of degrees cooler.
Listen to the RTÉ Rugby podcast on Apple Podcasts, Spotify or wherever you get your podcasts, and email us at sportpodcasts@rte.ie
Table
Munster, like the rest of the provinces, are without their Ireland contingent for this weekend's games and they face a Glasgow outfit that has only lost twice at this venue since December 2023.
Clayton McMillan's side are also without a number on players through injury, including JJ Hanrahan, Alex Nankivell and Jean Kleyn.
Ireland Under-20s out-half Tom Wood, son of Keith, is in line for a debut off the bench, while they have made four personnel changes and two positional switches to the side that beat Dragons last weekend as they ended a four-game losing streak.
The Scots, champions in 2024, lead the table on 39 points with eight wins from their 10 matches.
Glasgow have won their last two matches against Munster and have not won three in a row in the series since 2014.
Their only defeat in their last eight United Rugby Championship matches was 23-0 at the Scarlets in Round 6.
Munster: Mike Haley; Thaakir Abrahams, Shane Daly, Dan Kelly, Diarmuid Kilgallen; Tony Butler, Ethan Coughlan; Josh Wycherley, Diarmuid Barron (capt), Oli Jager; Evan O'Connell, Fineen Wycherley; Seán Edogbo, Ruadhán Quinn, Brian Gleeson.
Replacements: Lee Barron, Mark Donnelly, John Ryan, Gavin Coombes, Jack O'Donoghue, Paddy Patterson, Tom Wood, Seán O’Brien.
Glasgow Warriors: Josh McKay; Kyle Rowe, Stafford McDowall (capt), Kerr Yule, Ollie Smith; Dan Lancaster, Ben Afshar; Jamie Bhatti, Seb Stephen, Murphy Walker; Alex Craig, Jare Oguntibeju; Euan Ferrie, Angus Fraser, Ally Miller.
Replacements: Grant Stewart, Nathan McBeth, Sam Talakai, Dylan Cockburn, Sione Vailanu, Macenzzie Duncan, Jack Oliver, Matthew Urwin.
Referee: Craig Evans (WRU)
Connacht travel to Parma on the back of a disappointing 34-23 defeat to Leinster as they opened up their new-look Dexcom Stadium.
It was a seventh defeat in nine URC games for Stuart Lancaster's men, who start the round in 14th place, four points ahead of bottom side Zebre.
The Westerners have won just once away from home in the league since October 2024: 22-12 against today's opponents in May.
Massimo Brunello's men have lost their last eight URC matches after opening the season with a pair of victories.
Zebre have hosted Connacht in Parma on 13 occasions and won just twice, in April and December 2017.
Zebre Parma: Giovanni Montemauri; Mirko Belloni, Giulio Bertaccini, Marco Zanon, Simone Gesi; Martin Roger Farias, Gonzalo Garcia; Paolo Buonfiglio, Giampietro Ribaldi, Enrique Pieretto; Matteo Canali, Leonard Krumov (capt); Giacomo Ferrari, Iacopo Bianchi, Davide Ruggeri.
Replacements: Shilo Klein, Luca Franceschetto, Juan Pitinari, Franco Carrera, Alessandro Ortombina, Thomas Dominguez, Enrico Lucchin, Bautista Stavile.
Connacht: Sam Gilbert; Shane Jennings, Harry West, Cathal Forde, Chay Mullins; Josh Ioane, Caolin Blade; Jordan Duggan, Dylan Tierney-Martin, Jack Aungier; Josh Murphy, Joe Joyce; Paul Boyle (capt), Sean O'Brien, Sean Jansen
Replacements: Matthew Victory, Peter Dooley, Fiachna Barrett, David O’Connor, Niall Murray, Ben Murphy, Sean Naughton, Oisín McCormack.
Referee: Ben Whitehouse (WRU)
Leinster are looking to make it 11 wins in a row in all competitions with Edinburgh, the team's opponents in the last-16 of the Champions Cup in April, the visitors.
Since losing three of their opening four matches, Leo Cullen's side have ground out the victories to move to third in the table.
They have won their last five matches against Scottish opposition in all competitions since Glasgow beat them in the opening round of the 2023/24 URC season.
Leinster's only defeat at Aviva Stadium since May 2023 was the European semi-final loss to Northampton last May.
Edinburgh's single point defeat at Munster in Round 3 ended a run of three successive victories on visits to Ireland, while they haven't beaten Leinster since March 2019.
The Scottish side have visited this venue just once before, for the semi-final of the European Cup in 2012, losing 22-19 against Ulster.
Leinster: Andrew Osborne; Joshua Kenny, Rieko Ioane, Ciarán Mangan, Ruben Moloney; Charlie Tector, Luke McGrath (capt); Jerry Cahir, John Mckee, Andrew Sparrow; RG Snyman, Brian Deeny; Max Deegan, Scott Penny, Diarmuid Mangan.
Replacements: Gus McCarthy, Alex Usanov, Niall Smyth, Conor O'Tighearnaigh, Josh Ericson, Will Connors, Fintan Gunne, Hugo McLaughlin.
Edinburgh: Harry Paterson; Malelili Satala, Wes Goosen, James Lang, Duhan van der Merwe; Ross Thompson, Ben Vellacott; Boan Venter; Jerry Blyth-Lafferty, Paul Hill; Callum Hunter-Hill, Glen Young; Ben Muncaster, Freddy Douglas, Magnus Bradbury (capt).
Replacements: Harri Morris, Mikey Jones, Ollie Blyth-Lafferty, Tom Dodd, Connor Boyle, Charlie Shiel, Cammy Scott, Piers O'Conor.
Referee: Andrea Piardi (FIR)
Ulster welcome Cardiff to Belfast off the back of an impressive opening block of games, which has seen Richie Murphy's side recording six wins from nine matches.
It would have been even better had they seen out the late stages of last weekend's match at Scarlets when they conceded a try in overtime to lose 27-22.
However, it's been a largely positive spell for the province, who have played a game less due to a postponement in round two. That game against Edinburgh has been refixed for 13 March.
Ulster have won all six home games they have played in the 2025/26 season, while the Cardiff have not won in Ireland since beating Connacht 17-15 in Galway in September 2017.
Matt Sherratt's side have, however, won their last two matches against Ulster and have not won three in a row in the series since April 2010.
The Welsh outfit have been victorious at Affidea Stadium on just three occasions, on consecutive visits in May 2008, April 2009 and April 2010.
Ulster: Ethan McIlroy; Werner Kok, James Hume, Ben Carson, Zac Ward; Jack Murphy, Conor McKee; Angus Bell, Rob Herring, Scott Wilson; Iain Henderson (capt), Charlie Irvine; Matthew Dalton, Marcus Rea, David McCann.
Replacements: James McCormick, Sam Crean, Bryan O'Connor, Harry Sheridan, Lorcan McLoughlin, David Shanahan, Jake Flannery, Ben Moxham.
Cardiff: Cam Winnett; Ioan Lloyd, Harri Millard, Steffan Emanuel, Tom Bowen; Callum Sheedy, Johan Mulder; Rhys Barratt, Evan Lloyd, Javan Sebastian; Josh McNally (capt), George Nott; Alun Lawrence, Dan Thomas, Taine Basham.
Replacements: Daf Hughes, Danny Southworth, Joe Cowell, Rory Thornton, Lucas de la Rua, Aled Davies, Elijah Evans, Leigh Halfpenny.
Referee: Hollie Davidson (SRU)
FULL LIST OF FIXTURES, RESULTS AND STANDINGS
Follow every Ireland game in the Guinness Six Nations on RTÉ.ie/Sport and the RTÉ News app, or listen to live commentary on RTÉ Radio 1.
Watch live coverage of England v Ireland (21 February) and Ireland v Wales (6 March) on RTÉ2 and RTÉ Player.