Leo Cullen has rested a number of frontline internationals for Friday night's United Rugby Championship clash with Ulster at Aviva Stadium, making 11 changes from the team that battled past Leicester last week.
Only James Lowe, Jack Conan, Rieko Ioane and James Ryan survive from the starting XV at Welford Road, with the latter in line to earn his 100th cap.
"James has been club captain here in the past and is such a pivotal part of the group... We would have seen James come through from when he was playing in school.
"I saw footage this week of him against Will Conners' Clongowes team, they would have played against each other. I remember being down in Donnybrook that day watching those guys in action, so to see him come through and see what he has achieved... So big day for him," Cullen said of Ryan's 100th cap.
Conan captains the side at number eight, with Scott Penny and Alex Soroka on the flanks.
Ryan is joined in the engine room by Brian Deeny.
In the front row, Jack Boyle and Rabah Slimani will scrum down either side of Gus McCarthy, who has been named at hooker.
Ioane will make his first appearance in the URC outside of Charlie Tector in the centre, with out-half Sam Prendergast partnering Luke McGrath at scrum-half.
Ciarán Frawley has been named at 15 after coming off the bench to slot in at full-back for most of last Friday's 23-15 comeback win over the Tigers, with Lowe and Joshua Kenny on the wings.
Dan Sheehan, Paddy McCarthy and Tadhg Furlong will provide the front row cover for tomorrow night's game, with Joe McCarthy and Max Deegan completing the forward replacements.
Cullen does admit that Ulster have been travelling well this year and is hoping for a large Aviva Stadium crowd to help his side take the win.
"Really tough challenge for us against ulster this week, they have been travelling particularly well and scoring plenty of tries, so hopefully we get a big crowd down at the Aviva... The games are coming thick and fast at this time of year and hopefully we can put in a good performance," he said.
Fintan Gunne and Harry Byrne are the reserve half-backs and Ruben Moloney completes the matchday squad.
For the visitors, Australian international prop, Angus Bell, is set to make his first start for the province, while Ireland centre Stuart McCloskey returns from a recent groin injury to start at 12.
Among the replacements, Ethan McIlroy is in line for a first appearance since suffering an ACL injury in January.
In the front row, Bell is joined by Ireland international forwards in hooker, Tom Stewart, and tighthead prop, Tom O'Toole.
Harry Sheridan and Charlie Irvine continue to start together in the second-row .
David McCann starts at blindside flanker, with Nick Timoney captaining the team at openside flanker. South African forward, Juarno Augustus, starts at number eight.
Scrum-half Nathan Doak and fly-half Jack Murphy return to resume their partnership in the half back positions.
Head coach Richie Murphy selects two wingers in top try scoring form, with Werner Kok on the left and Robert Baloucoune on the right. Both wings have scored five tries each this season for the province.
McCloskey makes a welcome return to the side in the midfield, alongside Jude Postlethwaite at outside centre.
Ireland international, Jacob Stockdale, completes the XV at full-back.
Murphy opts for a 5:3 split among the replacements, which features a blend of experience and young talent.
John Andrew, Sam Crean, Scott Wilson, Joe Hopes and Academy back-row, Bryn Ward, form the forward replacements, with Conor McKee, Jake Flannery and McIlroy the backline cover options.
Leinster Rugby: Ciarán Frawley; Joshua Kenny, Rieko Ioane, Charlie Tector, James Lowe; Sam Prendergast, Luke McGrath; Jack Boyle, Gus McCarthy, Rabah Slimani; Brian Deeny, James Ryan; Alex Soroka, Scott Penny, Jack Conan (Capt)
Replacements: Dan Sheehan, Paddy McCarthy, Tadhg Furlong, Joe McCarthy, Max Deegan, Fintan Gunne, Harry Byrne, Ruben Moloney
Ulster Rugby: Jacob Stockdale; Rob Baloucoune, Jude Postlethwaite, Stuart McCloskey, Werner Kok; Jack Murphy, Nathan Doak; Angus Bell, Tom Stewart, Tom O'Toole; Harry Sheridan, Charlie Irvine; David McCann, Nick Timoney (Capt), Juarno Augustus
Replacements: John Andrew, Sam Crean, Scott Wilson, Joe Hopes, Bryn Ward, Conor McKee, Jake Flannery, Ethan McIlroy
Clayton McMillan has made six personnel and two positional changes to the Munster side that claimed a bonus-point win over Gloucester at Páirc Uí Chaoimh in the Champions Cup.
There are three changes in both the forwards and backs, with Jeremy Loughman, Fineen Wycherley, Alex Kendellen, Paddy Patterson, Tom Farrell, and Calvin Nash all coming into the starting XV.
Loughman joins Niall Scannell and Michael Ala'alatoa in the front row, while Jean Kleyn partners Wycherley in the second row. Kendellen slots in at openside flanker, with captain Jack O’Donoghue shifting to blindside and Gavin Coombes continuing at number eight.
A new half-back pairing sees Patterson link up with Jack Crowley, while Farrell partners Alex Nankivell in midfield. In the back three, Shane Daly moves to the left wing, Nash takes the right for his second appearance of the season, and Mike Haley retains the full-back jersey.
On the bench, Lee Barron, Michael Milne, Conor Bartley, Edwin Edogbo, Tom Ahern, and John Hodnett provide forward cover, while Ethan Coughlan and JJ Hanrahan are named among the backs replacements.
Munster Rugby: Mike Haley; Calvin Nash, Tom Farrell, Alex Nankivell, Shane Daly; Jack Crowley, Paddy Patterson; Jeremy Loughman, Niall Scannell, Michael Ala’alatoa; Jean Kleyn, Fineen Wycherley; Jack O’Donoghue (C), Alex Kendellen, Gavin Coombes.
Replacements: Lee Barron, Michael Milne, Conor Bartley, Edwin Edogbo, Tom Ahern, Ethan Coughlan, JJ Hanrahan, John Hodnett.
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Head coach Stuart Lancaster has made three changes to the team that defeated Black Lion in the Challenge Cup last week for the clash with the Dragons at Rodney Parade.
Cian Prendergast, Josh Ioane and Bundee Aki all return to the side.
Prendergast and Ioane have recovered from injuries in recent weeks, while Aki has returned from a down week.
Otherwise it's as selected, meaning a tight five of props Jordan Duggan and Sam Illo, hooker Dave Heffernan, and Roscommon brothers Darragh and Niall Murray in the second row.
Prendergast (above) comes in at blindside flanker to captain the side, with Sean O'Brien swapping to openside.
Caolin Blade continues at scrum-half, while Cathal Forde moves to outside centre alongside Aki.
There’s no change to the back three, with full-back Sam Gilbert and wingers Shayne Bolton and Chay Mullins.
Finlay Bealham features on the bench having overcome a head injury against the Ospreys.
Connacht: Sam Gilbert, Chay Mullins, Cathal Forde, Bundee Aki, Shayne Bolton, Josh Ioane, Caolin Blade, Jordan Duggan, Dave Heffernan, Sam Illo, Darragh Murray, Niall Murray, Cian Prendergast (C), Sean O’Brien, Paul Boyle.
Replacements: Dylan Tierney-Martin, Denis Buckley, Finlay Bealham, Josh Murphy, Sean Jansen, Ben Murphy, Jack Carty, Hugh Gavin.
