Scarlets centre Joe Roberts will make his first professional start on the wing when Wales tackle Guinness Six Nations title contenders England in Cardiff.
Roberts replaces Tom Rogers, who suffered a fractured thumb during the early stages of Wales' 35-29 defeat against Scotland at Murrayfield.
Wales’ interim head coach Matt Sherratt has made one other change from that game, with Aaron Wainwright featuring at blindside flanker for the 4.45pm kick-off on Saturday.
Wainwright’s call-up means captain Jac Morgan switches to his more familiar openside role and Leicester flanker Tommy Reffell drops to the replacements’ bench.
Roberts impressed on the wing after going on for Rogers in Edinburgh to win his fourth cap and he has won Sherratt’s vote ahead of other options such as starting Gloucester back Josh Hathaway or moving Max Llewellyn from midfield.
Yesterday, England made extensive changes to their team, including recalling Marcus Smith at full-back.
Wales: Blair Murray; Ellis Mee, Max Llewellyn, Ben Thomas, Joe Roberts; Gareth Anscombe, Tomos Williams; Nicky Smith, Elliot Dee, WillGriff John; Dafydd Jenkins, Will Rowlands, Jac Morgan (capt), Aaron Wainwright, Taulupe Faletau.
Replacements: Dewi Lake, Gareth Thomas, Keiron Assiratti, Teddy Williams, Tommy Reffell, Rhodri Williams, Jarrod Evans, Nick Tompkins.
England: Marcus Smith; Tom Roebuck, Tommy Freeman, Fraser Dingwall, Elliot Daly; Fin Smith, Alex Mitchell; Ellis Genge, Luke Cowan-Dickie, Will Stuart; Maro Itoje (capt), Ollie Chessum; Tom Curry, Ben Curry, Ben Earl.
Replacements: Jamie George, Fin Baxter, Joe Heyes, Chandler Cunningham-South, Henry Pollock, Tom Willis, Jack van Poortvliet, George Ford.
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Watch Italy v Ireland (from 1.15pm) and France v Scotland (from 7.30pm) in the Guinness Six Nations on RTÉ2 and RTÉ Player this Saturday.
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