Rónan Kelleher has been passed fit for Ireland, while Tadhg Furlong misses out on Friday's clash against New Zealand.
Kelleher has recovered from an ankle injury and takes his place at hooker for the 8.10pm kick-off at Aviva Stadium.
However, Leinster team-mate Furlong misses out with a hamstring injury with Connacht's Finlay Bealham, winning his 43rd cap, starting at tighthead.
"He had a bit of a slight hamstring strain coming into camp," head coach Andy Farrell told RTÉ Sport.
"He didn't play in [the] last Leinster game before coming into camp.
"We thought it would be something that would progress. He was rehabbing... and unfortunately it's just not picked up in time.
"Rather than push too hard and him be out for the series, we'll take our time and hopefully he's back sooner rather than later.
"He's had a good week as far as next steps etc but there's a process that you have to go through."
On hookers Kelleher and Rob Herring, who hasn't played for Ulster this season, Farrell added: "Rónan and Rob have done everything since we've come into camp so we are really pleased with that."
Elsewhere, the team is along expected lines with captain Caelan Doris at number 8, and Jack Crowley at out-half.
Hugo Keenan, Mack Hansen and James Lowe start in the Ireland back three, with Bundee Aki partnering Garry Ringrose in midfield, while Jamison Gibson-Park returns to the number 9 jersey alongside Crowley at out-half.
In the pack, Andrew Porter, Kelleher and Bealham are in the front row, with Joe McCarthy and James Ryan starting in the second row.
Tadhg Beirne is at blindside flanker, Josh van der Flier is at openside and Doris completes the starting XV.
Herring, Cian Healy, Tom O'Toole are the front row cover on the bench, while Iain Henderson and Peter O’Mahony are the other forward reinforcements
Conor Murray, Ciaran Frawley and Jamie Osborne are the backline options.
On the selection of Osborne among the back replacements ahead of Robbie Henshaw, Farrell said: "Unfortunately for Robbie, that's just the timing of things, we know what a world-class player he is.
"With the week's training under his belt that he's just had, he was very good actually in the training camp and it will set him up for future game over the next month."
Farrell (above) said: "I am really pleased with the effort of the squad across the week’s training camp in Portugal.
"Since assembling at the IRFU High Performance Centre last week, the players have brought real application to training and it’s great to see a number of players back from injury, which is testament to their diligence and the superb work of the medical team.
"It’s a hugely exciting four weeks ahead in Aviva Stadium and we know we’ll need to perform at a high level to beat a top-class New Zealand side.
"The challenge doesn’t come much bigger or better than New Zealand at a packed Aviva Stadium on a Friday night, under lights, with a home crowd roaring us on."
New Zealand have made two changes, with Damian McKenzie and Asafo Aumua coming in as expected.
McKenzie starts at out-half with Beauden Barrett ruled out due to concussion, while Aumua replaces Codie Taylor at hooker, who also suffered a heady injury in the 24-22 win against England on Saturday.
George Bell will provide front row cover on the bench, while Stephen Perofeta takes the 23 shirt.
Ireland: Hugo Keenan; Mack Hansen, Garry Ringrose, Bundee Aki, James Lowe; Jack Crowley, Jamison Gibson-Park; Andrew Porter, Rónan Kelleher, Finlay Bealham; Joe McCarthy, James Ryan; Tadhg Beirne, Josh van der Flier, Caelan Doris (capt).
Replacements: Rob Herring, Cian Healy, Tom O'Toole, Iain Henderson, Peter O'Mahony, Conor Murray, Ciarán Frawley, Jamie Osborne.
New Zealand: Will Jordan; Mark Tele'a, Rieko Ioane, Jordie Barrett, Caleb Clarke; Damian McKenzie, Cortez Ratima; Tamatai Willians, Asafo Aumua, Tyrel Lomax; Scott Barrett, Tupou Vaa'i; Wallace Sititi, Sam Cane, Ardie Savea
Replacements: George Bell, Ofa Tu'ungafasi, Pasilio Tosi, Patrick Tuipulotu, Samipeni Finau, Cam Roigard, Anton Lienert-Brown, Stephen Perofeta
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