The European action gets back under way this weekend with all four Irish provinces in action.
Leinster and Munster have reached the last 16 of the Investec Champions Cup and face Leicester and Northampton, respectively.
The Challenge Cup is the target for Ulster and Connacht with both side's meeting French opposition, Montpellier and Pau, on Sunday.
Find out all you need to know about the games here.
ONLINE
We'll have live blogs, live scoring, reports and reaction across the weekend on www.rte.ie/sport and the RTÉ News app.
TV
Leinster v Leicester (Saturday 8pm) is live on RTÉ2 and RTÉ Player on Saturday, with coverage getting under way at 7.30pm.
Northampton v Munster (Sunday 12.30pm) is on TNT, while Montpellier v Ulster (Sunday 3pm) and Pau v Connacht (Sunday 5.30pm) will be shown on Premier Sports and Viaplay.
RADIO
There will be live commentary of Leinster v Leicester on RTÉ Radio 1.
WEATHER
Dublin is set for partly cloudy and windy conditions on Saturday night in about 12C. Northampton will see higher temperatures on Sunday afternoon with 18C forecast in overcast conditions. It's set to be dry in Montpellier with sunshine and 19C, while it will be mostly cloudy in about 22C in Pau on Sunday.
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Four-time champions Leinster welcome the Tigers to Lansdowne Road for the team's seventh meeting in the knock-out stages.
They are familiar foes after meeting in the final round of the pool stages, a game Leinster won 27-10 at Welford Road to top their group.
The hosts are top of the URC standings and will look to continue the form that saw them record a superb 47-14 victory over Bulls last weekend.
Dan McKellar's Tigers are seventh in the Premiership and haven't beaten Leinster in 16 years.
Garry Ringrose is missing for the favourites but Hugo Keenan, Robbie Henshaw and Andrew Porter have all been passed fit.
Former Munster prop James Cronin starts for the visitors, who also boast Freddie Steward and Handre Pollard in their backline.
Leinster: Hugo Keenan; Jordan Larmour, Robbie Henshaw, Jamie Osborne, James Lowe; Ross Byrne, Jamison Gibson-Park; Andrew Porter, Dan Sheehan, Tadhg Furlong; Ross Molony, Joe McCarthy; Ryan Baird, Josh van der Flier, Caelan Doris (capt).
Replacements: Rónan Kelleher, Cian Healy, Michael Ala'alatoa, Jason Jenkins, Jack Conan, Ben Murphy, Harry Byrne, Ciarán Frawley.
Leicester: Jamie Shillcock; Freddie Steward, Dan Kelly, Solomone Kata, Ollie Hassell-Collins; Handré Pollard, Jack van Poortvliet; James Cronin, Julián Montoya (capt), Dan Cole; Harry Wells, Kyle Hatherell; Hanro Liebenberg, Olly Cracknell, Jasper Wiese.
Replacements: Charlie Clare, Francois van Wyk, Will Hurd, Finn Carnduff, Emeka Ilione, Tom Whiteley, Phil Cokanasiga, Mike Brown.
Referee: Pierre Brousset (FRA)
Munster face a trip to Franklin's Gardens for a repeat of their final pool game, which the 14-man Saints won 26-23 at Thomond Park.
Graham Rowntree’s side have had an inconsistent season and suffered defeat to Exeter and drew with Bayonne in the group stages.
But they come into this fixture on the back of URC victories over Cardiff, Ospreys, Zebre and Scarlets.
RG Snyman and Shane Daly were ruled out of contention on Saturday, while Calvin Nash misses out with a leg injury.
The Saints lead the Premiership and beat Saracens last weekend. Lewis Ludlam captains the hosts and Courtney Lawes is in the back row.
Northampton: James Ramm; Tommy Freeman, Fraser Dingwall, Burger Odendaal, Ollie Sleightholme; Fin Smith, Tom James; Emmanuel Iyogun, Curtis Langdon, Trevor Davison; Alex Moon, Alex Coles; Courtney Lawes, Lewis Ludlam (capt), Sam Graham.
Replacements: Sam Matavesi, Alex Waller, Paul Hill, Temo Mayanavanua, Angus Scott-Young, Juarno Augustus, Alex Mitchell, George Hendy.
Munster: Mike Haley; Simon Zebo, Antoine Frisch, Alex Nankivell, Seán O'Brien; Jack Crowley, Craig Casey; Jeremy Loughman, Niall Scannell, Stephen Archer; Tadhg Beirne (capt), Tom Ahern; Peter O'Mahony, John Hodnett, Gavin Coombes.
Replacements: Eoghan Clarke, Josh Wycherley, Mark Donnelly, Jack O’Donoghue, Alex Kendellen, Conor Murray, Joey Carbery, Shay McCarthy.
Referee: Mike Adamson (SCO)
Montpellier welcome Richie Murphy's Ulster to the GGL Stadium for their last-16 Challenge Cup clash on Sunday afternoon.
However, the French giants are in a relegation battle in the Top14 and the word on the street is this is a game they could do without.
Ulster, on the other hand, are just back from a double-header defeat in South Africa, and could see this competition as a real achievable goal having dropped down from the Champions Cup after a horrendous defeat to Harlequins under former boss Dan McFarland.
Iain Henderson, Rob Herring and Steven Kitshoff start in the pack, while Nathan Doak continues at out-half.
The hosts have also lost their last two games, at home to Stade and away to Toulon. Former England forward Sam Simmonds starts with Paul Willemse captaining the team.
Montpellier: Alexandre de Nardi; Gabriel N'Gandebe, George Bridge, Auguste Cadot, Ben Lam; Louis Foursans-Bourdette, Aubin Eymeri; Gregory Fichten, Christopher Tolofua, Harry Williams; Florian Verhaeghe, Paul Willemse (capt); Alex Becognee, Clement Doumenc, Sam Simmonds.
Replacements: Vano Karkadze, Baptiste Erdocio, Lasha Macharashvili, Tyler DuGuid, Yacouba Camara, Louis Carbonel, Masi Dakuwaqa, Pierre Lucas.
Ulster: Stewart Moore; Rob Baloucoune, James Hume, Stuart McCloskey, Ethan McIlroy; Nathan Doak, John Cooney; Steven Kitshoff, Rob Herring, Tom O'Toole; Alan O'Connor, Iain Henderson (capt); Matty Rea, David McCann, Nick Timoney.
Replacements: Tom Stewart, Andy Warwick, Scott Wilson, Harry Sheridan, Cormac Izuchukwu, Jake Flannery, Jacob Stockdale, Dave Ewers.
Referee: Craig Evans (WAL)
Pete Wilkins' Connacht face a trip to the south-west of France for their Challenge Cup last-16 tie.
Pau are currently seventh in the Top14, just one place off the play-offs and lost narrowly to Toulouse last weekend, 31-29.
The visitors, who dropped down from the Champions Cup, find themselves outside of the play-off places in the URC after recent defeats to Benetton and the Lions.
They are boosted by the return of Ireland internationals Bundee Aki and Finlay Bealham.
Former Wasps and England scrum-half Dan Robson starts for the hosts.
Section Paloise: Jack Maddocks; Thomas Carol, Eliott Roudil, Jale Vatubua, Aminiasi Tuimaba; Joe Simmonds, Dan Robson; Ziggy Fisi'ihoi, Youri Delhommel, Siate Tokolahi; Guillaume Ducat, Lekima Tagitagivalu; Martin Puech (capt), Thibaut Hamonou, Sacha Zegueur.
Replacements: Lucas Rey, Hugo Parrou, Guram Papidze, Steve Cummins, Fabrice Metz, Reece Hewat, Thibault Daubagna, Axel Desperes.
Connacht: Tiernan O'Halloran; Shayne Bolton, David Hawkshaw, Bundee Aki, Shane Jennings; Jack Carty (capt), Caolin Blade; Denis Buckley, Dave Heffernan, Finlay Bealham; Joe Joyce, Niall Murray; Cian Prendergast, Shamus Hurley Langton, Jarrad Butler.
Replacements: Eoin de Buitléar, Jordan Duggan, Sam Illo, Darragh Murray, Conor Oliver, Matthew Devine, JJ Hanrahan, Tom Farrell.
Referee: Andrea Piardi (ITA)
FULL LIST OF FIXTURES AND RESULTS FOR CHAMPIONS CUP AND CHALLENGE CUP
