Emmanuel Meafou is one of three new caps in the France side to face Wales in Sunday's Guinness Six Nations clash in Cardiff, with Fabien Galthie making seven changes to his team named on Friday.
Lock Meafou, 25, comes in for Posolo Tuilagi, out through illness, while Leo Barre makes his debut at fullback with Thomas Ramos moving to out-half in place of the injured Matthieu Jalibert.
Centre Nicolas Depoortere is the other debutant as he fills in for the suspended Jonathan Danty, who was sent off in the 13-13 draw with Italy.
Louis Bielle-Biarrey and Gregory Alldritt both return from injury after missing the game with Italy, and Nolann Le Garrec is preferred at scrumhalf with Maxime Lucu dropping to the bench.
Julien Marchand is chosen ahead of hooker Peato Mauvaka who is among the replacements. France are fourth in the standings on six points after one win, one draw and one defeat while Wales are three points behind in fifth with three defeats.
Team: Leo Barre, Damian Penaud, Gael Fickou, Nicolas Depoortere, Louis Bielle-Biarrey; Thomas Ramos, Nolann Le Garrec; Cyril Baille, Julien Marchand, Uini Atonio, Thibaud Flament, Emmanuel Meafou, Francois Cros, Charles Ollivon, Gregory Alldritt.
Replacements: Peato Mauvaka, Sebastien Taofifenua, Georges-Henri Colombe, Romain Taofifenua, Alexandre Roumat, Paul Boudehent, Maxime Lucu, Yoram Moefana.
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Watch England v Ireland in the Guinness Six Nations on Saturday from 4pm on RTÉ2 and RTÉ Player, follow a live blog on rte.ie/sport and the RTÉ News app and listen to live commentary on RTÉ Radio 1
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