Leo Cullen says last month's 57-0 win against Gloucester bears little relevance to the challenge faced on Saturday when the sides meet at Kingsholm.
The province barely left third gear in their nine-try win against the Premiership side in Round 2 at the RDS, with Gloucester having fielded a second-string team in order to prioritise their domestic fixtures.
Qualification for the last 16 remains possible for the Cherry and Whites, and head coach George Skivington has made 14 changes to the side that played in Dublin.
Jonny May, Chris Harris, Ollie Thorley, Val Rapava Ruskin, George McGuigan and captain Lewis Ludlow all start in a side that looks close to full strength, aside from injured pair Adam Hastings and Louis Rees-Zammit.
"We expect something totally different," Cullen said, when asked about the challenge facing Leinster at Kingsholm.
"Gloucester sent a weakened team to Dublin, so t's a totally different set of players this week.
"All of the things we spoke of in the lead-up to our last game still apply. Gloucester are a very proud club and proud team, and are well coached with strong fundamentals. It will be a very tough game for our guys tomorrow."
It's a second trip to Kingsholm in the space of a week for Cullen (below), who stopped off to watch Gloucester's defeat to Saracens a week ago before heading on to Swansea for Leinster's URC meeting with the Ospreys.
And he says that trip provided a good opportunity to learn a bit more about this week's opponents.
"I went to watch them play Saracens last week with a few of our coaching gang, and it's a totally different proposition.
"We just get a better sense of the surroundings. I hadn't been there since they put the astro down, and you just get a gauge for the setup. We were in Ospreys on the Saturday, so it made sense for us to go.
"Kingsholm, the Shed, the atmosphere, you get a flavour for it, and it was a proper full-blooded game against Saracens, real nip-and-tuck sort of game.
"Gloucester have strong fundamentals, they kick a lot from nine and chase hard, they're hard to break down defensively. It's going to be a very tough game for our team, but our guys prepared well this week.
"There are lots of sub-plots going on all across the weekend and next weekend there will be even more, all the calculators will be out.
"It's an early start tomorrow, so hopefully we'll be able to rip into it nice and early."
While Johnny Sexton and Tadhg Furlong remain sidelined with injury, Leinster have been able to welcome most of their frontline internationals back into their starting side, with Cian Healy set to become just the fifth player to make 100 appearances in the Champions Cup, joining Ronan O'Gara, Gordon D'Arcy, John Hayes and Peter Stringer on an all-Irish list of centurions.
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