Munster and Leinster have both named youthful looking squads for their United Rugby Championship clashes with Dragons and Benetton respectively.
Johann van Graan has made four changes to the Munster side that defeated Edinburgh two weeks ago as Shane Daly, Jack Crowley, Josh Wycherley and John Ryan all come into the starting XV.
Craig Casey and Gavin Coombes both keep their places after being released from Ireland's Six Nations camp for the clash.
Wycherley makes his first start of the season on his 17th appearance for the province and starts in the same pack as brother Fineen for the second time.
Haley starts at full-back with Daly and Simon Zebo on either flank.
Dan Goggin and Chris Farrell continue their centre partnership with Casey and Crowley in the half-backs.
Josh Wycherley, Diarmuid Barron and John Ryan pack down in the front row with Jean Kleyn and Fineen Wycherley in the second row.
Captain Jack O’Donoghue, Chris Cloete and Coombes complete the side.
Munster: Mike Haley; Shane Daly, Chris Farrell, Dan Goggin, Simon Zebo; Jack Crowley, Craig Casey; Josh Wycherley, Diarmuid Barron, John Ryan; Jean Kleyn, Fineen Wycherley; Jack O’Donoghue (C), Chris Cloete, Gavin Coombes.
Replacements: Niall Scannell, Jeremy Loughman, Stephen Archer, Alex Kendellen, John Hodnett, Neil Cronin, Ben Healy, Rory Scannell.
Dragons: Jordan Williams, Will Talbot-Davies, Jack Dixon, Aneurin Owen, Rio Dyer, Sam Davies, Rhodri Williams; Greg Bateman, Taylor Davies, Chris Coleman, Joe Davies, Joe Maksymiw, Harri Keddie (CAPT), Ollie Griffiths, Aaron Wainwright.
Replacements: Ellis Shipp, Aki Seiuli, Mesake Doge, Huw Taylor, Ben Fry, Dan Baker, Lewis Jones, Josh Lewis
Peter Dooley will make his 100th appearance for Leinster against Benetton at Stadio Monigo (KO 12.55pm Irish time - live on RTÉ 2 and RTÉ Player).
Offaly native Dooley made his debut for Leinster against Edinburgh Rugby in October 2014. The following season he played 21 times and has been an integral part of the squad since.
On this landmark occasion, he'll be joined in the front row by Seán Cronin and Thomas Clarkson.
Joe McCarthy retains his spot in the second row and is joined by Ross Molony who returns after spending time with the Ireland squad last week.
Rhys Ruddock, Scott Penny and Max Deegan complete the pack.
Captain for the trip to Treviso is Luke McGrath who dons the number nine, partnered by Ross Byrne in the half-backs.
Once more, Cullen and Co have opted for Harry Byrne and Jamie Osborne in the midfield while both Jordan Larmour and Jimmy O'Brien start having also returned from international duty for the tie.
Last week's player of the match Tommy O'Brien lines out on the left wing.
Leinster: Jimmy O'Brien; Jordan Larmour, Jamie Osborne, Harry Byrne, Tommy O'Brien; Ross Byrne, Luke McGrath capt); Peter Dooley, Seán Cronin, Thomas Clarkson, Ross Molony, Joe McCarthy, Rhys Ruddock, Scott Penny, Max Deegan
Replacements: James Tracy, Ed Byrne, Michael Ala'alatoa, Devin Toner, Dan Leavy, Cormac Foley, Rory O'Loughlin, Dave Kearney
Benetton: Andries Coetzee, Lorenzo Pani, Joaquin Riera, Filippo Drago, Rhyno Smith, Tomas Albornoz, Alessandro Garbisi, Federico Zani, Corniel Els, Nahuel Tetaz, Nicola Piantella, Carl Wegner (CAPT), Matteo Meggiato, Lorenzo Cannone, Toa Halafihi
Replacements: Tomas Baravalle, Matteo Drudi, Cherif Traore, Abraham Steyn, Alessandro Izekor, Luca Petrozzi, Marco Zanon, Luca Sperandio
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Follow all of Ireland's Six Nations games via our live blogs on rte.ie/sport and on the RTÉ News App or listen to live radio coverage on RTÉ Radio 1. Watch live coverage of England v Ireland on Saturday 12 March (4.45pm) on RTÉ2 and RTÉ Player.
Also, see live URC action this week with Ulster v Cardiff (Friday 4 March, 7pm) and Benetton v Leinster (Saturday 5 March, 12.30pm) live on RTÉ2 and RTÉ Player.
