Three Irish teams are already qualified for the last 16 heading into the final round of games, and the likelihood is that it will be a full house by Sunday evening.
Connacht joined Munster and Ulster in securing qualification earlier today, with the cancelation of Toulouse v Cardiff ensuring that Connacht couldn't be knocked out of the top eight in Pool B, regardless of what happens in their meeting with Stade Francais on Sunday.
Leinster are still yet to qualify though, and are still wounded by the concession of a 28-0 walkover to Montpellier in December.
However, they will be expected to do the business away to Bath in Saturday's early kick-off, which would see them qualify, as well as ensuring home advantage for the second leg of their last-16 tie.
For Munster and Ulster, with qualification assured their only focus is getting as high a seeding as possible. The top two in each pool get home advantage for the second leg of the last 16, while they would also have home advantage for a potential quarter-final.
A win of any kind for Ulster against Clermont on Saturday would see them be guaranteed a top two finish in Pool A, although they are unlikely to catch leaders Racing 92 who will be expected to take maximum points from their home meeting with Northampton.
For Munster to finish in the top two of Pool B, they will need to better the result of either Leicester Tigers or Harlequins, Johann van Graan's side welcome a rejuvenated Wasps to Thomond Park, with the English side bouncing from recent wins against Toulouse, having seen their injury troubles ease.
All games are live on BT Sport, while Bath v Leinster is also shown on Virgin Media and Channel 4.
Bath v Leinster is live in RTÉ Radio 1 and RTÉ Radio 1 Extra.
RTE.ie/sport will have live scoring and blogs with match reports and reaction from the grounds.
Conditions look promising for all four games involving the Irish sides this weekend. For Leinster's trip to Bath, it's likely to be cold but sunny, with temperatures around 4C, with very little wind. It's expected to be slightly breezier, but also a bit milder in Belfast, where Ulster take on Clermont Auvergne. On Sunday, Connacht fans travelling to Paris should expect dry afternoon with temperatures of 3-5C. It's expected to be quite calm in Limerick Sunday afternoon where Munster host Wasps, with a dry day expected and temperatures of 8-9C.
Leinster would have been expected to finish in the top two of Pool A, so their 28-0 concession to Montpellier in December will likely cost them home advantage for a potential quarter or semi-final.
A win of any kind at the Rec will ensure they advance to the Round of 16, but in reality even if they lose it would take a remarkable set of results for them to drop out of the top eight.
They cruised to a 45-20 win when the sides met in Round 1 at the viva Stadium, despite Leinster playing nowhere near their best rugby.
Bath remain firmly planted to the bottom of the Premiership table, although they did pick up their first win of the campaign earlier this month against Worcester.
Their European form in recent seasons is just as bleak, with Stuart Hooper's side on a 10-game losing streak in the Champions Cup.
This will be their 13th meeting in the competition, making Leinster Bath's most frequent opponent, but Leo Cullen's side have on 10 of the previous 12 meetings.
Bath: Ruaridh McConnochie; Gabe Hamer-Webb, Max Clark, Cameron Redpath, Tom Prydie; Orlando Bailey, Ben Spencer; Arthur Cordwell, Jacques du Toit, Will Stuart; Will Spencer, Charlie Ewels (capt); Tom Ellis, Sam Underhill, Josh Bayliss.
Replacements: Tom Doughty, Will Vaughan, Johannes Jonker, Josh McNally, Mike Williams, Joe Simpson, Max Ojomoh, Will Butt,
Leinster: Hugo Keenan; Jordan Larmour, Garry Ringrose, Robbie Henshaw, Jimmy O'Brien; Johnny Sexton (capt), Luke McGrath; Andrew Porter, Ronan Kelleher, Michael Ala'alatoa; Ross Molony, Josh Murphy; Caelan Doris, Josh van der Flier, Jack Conan.
Replacements: Dan Sheehan, Cian Healy, Vakh Abdaladze, Ryan Baird, Max Deegan, Jamison Gibson-Park, Ross Byrne, Ciaran Frawley
Ref: Andrea Piardi (Italy)
While they are already qualified, this game is far from a free hit for Dan McFarland's side.
The prize of home advantage later in the competition is far too great for them to become complacent, and a win of any kind will see them finish in the top two in Pool A.
Ulster's win at Stade Marcel Michelin surprised many, and they've since followed it up with back-to-back bonus point victories against the Northampton Saints, the most recent of which saw their backline sizzle in spite of the absence of John Cooney, Stuart McCloskey and Jacob Stockdale.
Consistency is Ulster's toughest opponent though, either side of their wins against Northampton was that disappointing second half performance against Munster.
The form book is encouraging for Ulster; they've won all three of their previous meetings with Clermont in Belfast, while they've won 10 of their last 11 home games in the competition.
Clermont are clinging on to a place in the top eight of the pool, so in theory there should be plenty of fight in their side. The French side have also been better away from home in recent seasons, winning their last four away games in this competition.
Their head coach Jono Gibbes will also be quite familiar with Ulster, having been in charge at Kingspan Stadium from 2017 to 2018.
Ulster: Mike Lowry; Robert Baloucoune, James Hume, Angus Curtis, Ethan McIlroy; Billy Burns, Nathan Doak; Eric O'Sullivan, Rob Herring, Marty Moore; Alan O’Connor (capt), Kieran Treadwell; Marcus Rea, Nick Timoney, Duane Vermeulen.
Replacements: John Andrew, Jack McGrath, Tom O’Toole, Sam Carter, Greg Jones, David Shanahan, Ben Moxham, Craig Gilroy
Clermont Auvergne: Cheik Tiberghien; Marvin O'Connor, Jean-Pascal Barraque, Tani Vili, Alivereti Raka; JJ Hanrahan, Morgan Parra; Etienne Falgoux, Yohan Beheregaray, Rabah Slimani; Paul Jedrasiak, Tomas Lavanini; Judicaël Cancoriet (capt), Lucas Dessaigne, Jacobus Van Tonder.
Replacements: Etienne Fourcade, Daniel Bibi Biziwu, Cristian Ojovan, Sébastien Vahaamahina, Fritz Lee, Kevin Viallard, Camille Lopez, Damian Penaud
Ref: Luke Pearce (England)
Following last week's agonising defeat to Leicester at the Sportsground, Connacht will be hoping to bounce back in style this Sunday against Stade Francais in Paris.
If they can produce anything close to a repeat of their previous encounter with Stade at the Sportsground in December, they should be well on their way to improving their seed for the knockout stages.
Andy Friend's side were 39-9 winners when the sides met in Round 1, with Stade playing a similar kicking game to the one Connacht will have faced in recent weeks against Leicester and Munster.
Another area of optimism for Connacht is the 4g pitch at Stade Jean-Bouin, which should provide an ideal platform for them to play the running game they are best suited to.
The French side have won 35 of their 36 home games in the pool stage of the Heineken Champions Cup, their only defeat coming against Harlequins in 2008/09 (10-15).
Meanwhile, Connacht have lost their last seven away games in the competition, but the last three defeats came by margins of fewer than seven points.
Stade look much stronger than their December line-up, with Ngani Laumape and Clement Castets adding bulk to their squad, while Connacht are without Finlay Bealham, Ultan Dillane, Kieran Marmion and Bundee Aki.
Stade Francais: Kylan Hamdaoui; Telusa Veainu, Ngani Laumape, Léo Barre, Adrien Lapegue; Nicolas Sanchez, William Percillier; Clément Castets, Tolu Latu, Paul Alo Emile; Mathieu De Giovanni, Paul Gabrillagues; Charlie Francoz, Sekou Macalou, Tala Gray (capt).
Replecements: Lucas Da Silva, Moses Alo Emile, Nemo Roelofse, Juan Johan Van der Mescht, Marcos Kremer, James Hall, Joris Segonds, Paul Champ
Connacht: Tiernan O'Halloran; Alex Wootton, Tom Farrell, Sammy Arnold, Mack Hansen; Jack Carty (capt), Caolin Blae; Jordan Duggan, Shane Delahunt, Greg McGrath; Oisín Dowling, Niall Murray; Cian Prendergast, Conor Oliver, Jarrad Butler
Replacements: Dave Heffernan, Charlie Ward, Sam Illo, Leva Fifita, Paul Boyle, Colm Reilly, Conor Fitzgerald, Diarmuid Kilgallen
Ref: Wayne Barnes (England)
Six weeks ago it looked like Munster's season had exploded into life when their patched-up team hammered Wasps in Coventry, but while they have won three of their four games since, their performances have not been convincing.
They scored four tries that afternoon, but have crossed the line just five times in the four games since.
Despite their performances, a place in the quarter final is already assured, with just their seeding left to be determined.
Wasps have picked themselves up from that defeat in December, and with the help of some key players returning from injury they have beaten Toulouse and Leicester Tigers in recent weeks.
However, they will be without out-half Jacob Umaga for the trip to Limerick, after his red card against the defending champions a week ago.
Sunday's game will be the sixth between the sides in this competition, with Munster leading the rivalry by three to two.
Munster: Mike Haley; Andrew Conway, Chris Farrell, Rory Scannell, Keith Earls; Ben Healy, Conor Murray; Dave Kilcoyne, Diarmuid Barron, Stephen Archer; Jean Kleyn, Tadhg Beirne; Peter O'Mahony (capt), Jack O'Donoghue, Gavin Coombes.
Replacements: Scott Buckley, Jeremy Loughman, John Ryan, Fineen Wycherley, John Hodnett, Craig Casey, Jack Crowley, Simon Zebo.
Wasps: Ali Crossdale; Marcus Watson, Paolo Odogwu, Ryan Mills, Josh Bassett; Charlie Atkinson, Dan Robson; Tom West, Tom Cruse, Elliott Millar-Mills; Elliott Stooke, James Gaskell; Brad Shields (capt), Thomas Young, Nizaam Carr.
Replacements: Gabriel Oghre, Rodrigo Martinez, Pieter Scholtz, Tim Cardall, Ben Morris, Will Porter, Rob Miller, Sam Spink
Ref: Tual Trainini (France)