Ireland head coach Adam Griggs has named three uncapped players in his squad for the upcoming World Cup qualifiers in Italy.
Lucy Mulhall, Ireland 7s captain, Ireland-qualified forward Sam Monaghan and Leinster's Mary Healy are all in line for a first appearance.
The team are vying for a spot in Group B of the Rugby World Cup, which will be played in New Zealand next year, having been delayed due to the pandemic.
Griggs' side face Spain, Italy and Scotland in a round-robin tournament being held in Parma from 13-25 September.
The winner earns automatic qualification with the runner-up entering a last-chance tournament.
"While we can only focus on one game at a time, we won't shy away from the end goal of this being a winner-takes-all tournament for participation at Rugby World Cup 2021," Griggs said.
"The players and staff are all highly motivated and focused on making sure we are successful as a group."
Back row Ciara Griffin will again captain the team, while Edel McMahon, who missed the Six Nations through injury, returns to the panel.
Ireland Squad (Rugby World Cup 2021 Europe Qualifier)
Enya Breen (UL Bohemian/Munster) (6 caps)
Eimear Considine (UL Bohemian/Munster) (18)
Kathryn Dane (Old Belvedere/Ulster) (13)
Lauren Delany (Sale Sharks/IQ Rugby) (14)
Stacey Flood (Railway Union/Leinster) (3)
Eve Higgins (Railway Union/Leinster) (3)
Emily Lane (Blackrock College/Munster) (3)
Ailsa Hughes (Railway Union/Leinster) (12)
Lucy Mulhall (Rathdrum/Leinster)*
Amee-Leigh Murphy Crowe (Railway Union/Munster) (2)
Sene Naoupu (Old Belvedere/Leinster) (41)
Beibhinn Parsons (Ballinasloe/Blackrock College/Connacht) (11)
Mary Healy (Naas RFC/Leinster)*
Linda Djougang (Old Belvedere/Leinster) (12)
Laura Feely (Blackrock College/Connacht) (19)
Nichola Fryday (Blackrock College/Connacht) (18)
Ciara Griffin (UL Bohemian/Munster)(Captain) (36)
Brittany Hogan (DCU/Old Belvedere/Ulster) (4)
Neve Jones (Malone/Ulster) (3)
Leah Lyons (Harlequins/IQ Rugby) (26)
Aoife McDermott (Railway Union/ Leinster) (16)
Edel McMahon (Wasps/IQ Rugby) (9)
Claire Molloy (Wasps/IQ Rugby) (71)
Cliodhna Moloney (Wasps/IQ Rugby) (26)
Sam Monaghan (Wasps/IQ Rugby)*
Katie O'Dwyer (Railway Union/Leinster) (3)
Lindsay Peat (Railway Union/Leinster) (34)
Dorothy Wall (Blackrock College/Munster) (7)
*Denotes uncapped at this level
RWC 2021 Europe Qualifier schedule
Monday, 13 September
Scotland v Italy (2pm Irish time)
Spain v Ireland (5pm)
Sunday, 19 September
Italy v Ireland (2pm)
Spain v Scotland (5pm)
Saturday, 25 September
Italy v Spain (2pm)
Ireland v Scotland (5pm)