Leinster will play their opening home game of the new United Rugby Championship at the Aviva Stadium amid concerns about capacity limits for season ticket holders at the RDS.
The province will also play a pre-season friendly against English Premiership side Harlequins on 10 September at the venue, with a 15,000 capacity set to be confirmed for the Aviva Stadium "in the coming weeks".
"At this moment in time, with the current restrictions in place and likely to be in place for at least another month, we would be unable to accommodate the over 12,000 season ticket holders that have committed to us for the season ahead in the RDS Arena," said Leinster CEO Mick Dawson.
"Until we can guarantee their tickets, it is very difficult to commit to games at the RDS Arena and we hope by announcing this decision now it gives clarity to supporters who might have been concerned about their purchase with the season less than a month away."
He added: "It should be noted that it is very much our intention to return to the RDS Arena when we can accommodate all of our season ticket holders but right now, with Covid-19 restrictions still very much a feature of the immediate sporting landscape we felt it was the right decision to take and crucially secures us much needed revenue after a very challenging 20 months."
However, Dawson said that the move to the Aviva is "under review" and could be extended to cover further fixtures.
"With an update from the Government coming potentially as early as next week, we can make further decisions on a potential return to the RDS Arena after that," he added.
RTÉ Sport and TG4 will broadcast over 50 free-to-air games for the inaugural United Rugby Championship which is due to kick-off in September.
