Stuart Hogg will captain an almost entirely new British and Irish Lions starting XV for their opening fixture in South Africa against the Gauteng Lions on Saturday.
Hogg was dropped by Exeter for the closing stages of their Gallagher Premiership title push but the Scotland skipper has been thrust into Warren Gatland's team at the first available opportunity.
The 29-year-old full-back only linked up with the squad after Saturday's Premiership final defeat by Harlequins and has been given an immediate chance to press for Test selection in Johannesburg.
He is joined in the back line by Scotland team-mate Finn Russell, who forms an intriguing 10-12 axis with Owen Farrell - one of his rivals for the out-half duties against the Springboks.
Russell has overcome an ankle injury to make his first appearance of the tour and is picked in a half-back partnership alongside compatriot Ali Price.
Josh Adams is the only survivor from last weekend's win against Japan in Edinburgh.
Six Ireland internationals started against the Japanese at Murrayfield but none are included this time. Bundee Aki and Iain Henderson are however named on the bench.
British and Irish Lions (v Gauteng Lions): Stuart Hogg (captain), Louis Rees-Zammit, Chris Harris, Owen Farrell, Josh Adams, Finn Russell, Ali Price; Wyn Jones, Jamie George, Kyle Sinckler, Maro Itoje, Jonny Hill, Courtney Lawes, Hamish Watson, Taulupe Faletau
Replacements: Luke Cowan-Dickie, Mako Vunipola, Zander Fagerson, Iain Henderson, Sam Simmonds, Gareth Davies, Bundee Aki, Elliot Daly