Rufus McLean received his maiden call-up to the senior Scotland side after coach Gregor Townsend named the Boston-born Glasgow Warriors full-back in his 34-man squad for Sunday's Six Nations game at home to Ireland.
Edinburgh number eight Nick Haining and Exeter Chiefs lock Sam Skinner were also included for the game at Murrayfield.
Scotland, who have five points after two games, will be without suspended fly-half Adam Hastings and prop Zander Ferguson. Richie Gray is also absent, having sustained a head injury during Glasgow's recent Pro14 defeat to Leinster.
Backs: Jamie Dobie, Darcy Graham, Chris Harris, Stuart Hogg, Sam Johnson, Huw Jones, James Lang, Sean Maitland, Rufus McLean, Duhan van der Merwe, Ali Price, Finn Russell, Scott Steele, Duncan Taylor, Jaco van der Walt.
Forwards: Ewan Ashman, Simon Berghan, Jamie Bhatti, Dave Cherry, Alex Craig, Scott Cummings, Mattt Fagerson, Grant Gilchrist, Jonny Gray, Nick Haining, Rob Harley, Oli Kebble, WP Nel, Cornell du Preez, Jamie Ritchie, Sam Skinner, Rory Sutherland, George Turner, Hamish Watson.
Follow Scotland v Ireland (kick-off 3pm, Sunday) via our live blog on RTE.ie and the RTÉ News app or listen live on RTÉ Radio 1's Sunday Sport. Highlights on Against the Head on RTÉ2 and RTÉ Player, 8pm Monday.