England have named George Ford at out-half in their only change for Saturday's Autumn Nations Cup clash with Wales at Parc y Scarlets.
Ford has been reinstated as playmaker-in-chief after making his comeback from an Achilles injury as a replacement in last weekend's resounding 18-7 victory over Ireland at Twickenham.
The midfield adjustment is partially a result of Ollie Lawrence suffering a hip problem and the knock-on effect is to see captain Owen Farrell join Henry Slade in the centres.
While the rest of the starting XV - including the pack that submitted Ireland in such brutal fashion - have been retained, Eddie Jones has made some adjustments to the bench.
Jack Willis is poised to win his second cap after being included in a six-two split between forwards and backs alongside fellow flanker Ben Earl and lock Jonny Hill.
Meanwhile Cardiff Blues scrum-half Lloyd Williams [above] will make his first Wales start for four years.
Flanker James Botham - grandson of England cricket great Ian Botham - retains his place in a back-row missing Justin Tipuric and Josh Navidi.
Tipuric suffered a head knock during the victory over Georgia last weekend, and Navidi remains unavailable as he continues his recovery from concussion.
Williams, who has won 30 caps, partners Dan Biggar at half-back, with Botham moving from blindside to openside flanker following a promising Test debut in the Georgia game.
Cardiff-born Botham is joined in the back-row by Shane Lewis-Hughes and Taulupe Faletau, and with centre Jonathan Davies sidelined due to a knee injury, Nick Tompkins and Johnny Williams again forge Wales' midfield combination.
Scarlets centre Williams qualifies for Wales through his father, who is from Rhyl. Williams represented England and scored a try in a non-cap game against the Barbarians last year.
Elsewhere, 19-year-old Gloucester wing Louis Rees-Zammit wins a third Test cap, Ryan Elias returns at hooker and captain Alun Wyn Jones is partnered in the second-row by Jake Ball, but full-back Liam Williams misses out.
Wales: L Halfpenny; J Adams, N Tompkins, J Williams, L Rees-Zammit; D Biggar, L Williams; W Jones, R Elias, S Lee, J Ball, A Wyn Jones, S Lewis-Hughes, J Botham, T Faletau.
Replacements: E Dee, R Carre, T Francis, W Rowlands, A Wainwright, R Webb, C Sheedy, O Watkin.
England: E Daly; J Joseph, H Slade, O Farrell (capt), J May; G Ford, B Youngs; M Vunipola, J George, K Sinckler, M Itoje, J Launchbury, T Curry, S Underhill, B Vunipola.
Replacements: L Cowan-Dickie, E Genge, W Stuart, J Hill, B Earl, J Willis, D Robson, A Watson.
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