Scotland's Autumn Nations Cup fixture with Fiji at Murrayfield on 28 November has been cancelled after the Pacific Islanders' squad was decimated by coronavirus.
Fiji have already seen their opening two matches against France and Italy called off after the latest round of Covid-19 tests produced 29 positive test results.
France were awarded a 28-0 win after their Group B opener was cancelled last Saturday and Gregor Townsend's Scots - who face Les Bleus on Sunday - will expect to be given the same.
A Scottish Rugby spokesperson said: "While this is very disappointing news, we support the decision to cancel the game and wish a speedy recovery to those affected in the Fijian squad.
Our focus remains fully on Sunday's match against France."
Fiji are now guaranteed to finish bottom of their pool without playing a game but tournament bosses are still hoping Vern Cotter's team can take part in the competition in the final round of games scheduled for 5 December.
In a statement, the organisers of the Autumn Nations Cup said: "The extent of infection in the Fiji camp, combined with a minimum 10-day isolation period, plus the obvious need for suitable preparation for any international Test match meant that, whilst difficult, the decision was unavoidable.
"The tournament organisers remain in constant contact with the Fijian squad regarding their wellbeing and recovery which continues to be the number one priority.
"The Fiji team and the organisers are hopeful that the fourth match on December 5th against the team that will finish in 4th place in Pool A will be able to take place, subject to checks on fitness levels once the players come out of isolation and following all appropriate protocols."
Meanwhile, Townsend has made five changes for the France match.
Les Bleus had been due to send a second-string line-up to Edinburgh but changed their mind after last week's the game with Fiji was called off.
Townsend will hope to put the brakes on a team he believes is in better form than even the All Blacks at present and has named a new front row with Oli Kebble, Fraser Brown and Simon Berghan packing down.
Matt Fagerson is next to be given the chance to stake a claim for Scotland's problematic number eight jersey after Blade Thomson did little to show he is the long-term pick at the back of the scrum, while the only change in the backs see wing Blair Kinghorn replace Edinburgh club-mate Darcy Graham.
France coach Fabien Galthie made eight changes to the team who beat Ireland in the Six Nations.
Matthieu Jalibert comes in at fly-half in the absence of the injured Romain Ntamack, alongside scrum-half Antoine Dupont, while Thomas Ramos, who will be on kicking duty, is in for the injured Anthony Bouthier at full-back.
Following an agreement between the French federation and the League, each player can be named on no more than three teamsheets during the November-December period, and Galthie has decided to bring in some of his usual replacements - or 'finishers' as he calls them - for the trip to Scotland.
The front row has been completely revamped, with Jean-Baptiste Gros, Camille Chat and Demba Bamba starting in place of Cyril Baille, Julien Marchand and Mohamed Haouas who played in the wins over Wales in a friendly and Ireland in the Six Nations finale.
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