Ulster's away game against Benetton Rugby this weekend has been postponed as the Italian authorities continue to grapple with the Coronavirus outbreak.
Both Pro14 fixtures which were due to take place in Italy on Saturday will be re-scheduled as Zebre's home game against Ospreys has also been postponed.
The restrictions on public gatherings and sporting events put in place by the Italian authorities apply in the Lombardy, Emilia-Romagna and Veneto regions and have already seen a Women's Six Nations game and four Serie A football fixtures postponed over the weekend.
Fixtures in Italy’s national rugby championship - Top 12 - and all domestic rugby activities have also been postponed ahead of this weekend.
The present restrictions are in place until Sunday 1 March.
Pro14 Rugby said they will remain in contact with the Italian rugby authorities and are continuing to monitor the situation.
"To ensure the safety of our players and spectators PRO14 Rugby fully supports the preventative measures taken in Italy and will adhere to the directives from the World Health Organisation (WHO) and local authorities," read a statement on the PRO14 website.
"The current restrictions are in place until March 1 and PRO14 Rugby will remain in contact with the FIR (Italian Union), Zebre Rugby Club, Benetton Rugby and World Rugby to monitor (the) situation on a daily basis."
An alternative date for the postponed fixtures has yet to be announced.
The IRFU said the Six Nations games against Italy in Ireland, on the weekend after next, are set to go ahead as scheduled.
The union said it will follow Government advice in relation to Covid-19.