Seán Cronin returns from injury and Tommy O'Brien makes his Leinster debut in Friday evening's Guinness Pro14 clash with Ulster at the RDS Arena.
It's a welcome return for Cronin who makes his first appearance of the season after recovering from a neck injury.
Debutant O'Brien is joined in the centre by Robbie Henshaw who is named in the number 12 jersey.
O'Brien, 21, has previously represented Ireland Under 20s (5 caps) and Leinster 'A' while he plays with UCD in the Energia All-Ireland League. He is a former Leinster Schools 110m hurdle champion while his father and sister represented Ireland in athletics.
The back three sees Rob Kearney start at full back, with Fergus McFadden and Cian Kelleher on the right and left wing respectively.
In the half-backs, Jamison Gibson-Park is joined by Harry Byrne who makes his second start for the team having also started against the Dragons last month.
Leinster: Rob Kearney, Fergus McFadden, Tommy O'Brien, Robbie Henshaw, Cian Kelleher, Harry Byrne, Jamison Gibson-Park, Peter Dooley, Seán Cronin, Andrew Porter, Scott Fardy, Josh Murphy, Will Connors, Scott Penny, Max Deegan
Replacements: Bryan Byrne, Cian Healy, Jack Aungier, Oisín Dowling, Josh van der Flier, Hugh O’Sullivan, Ciarán Frawley, Conor O’Brien
Alan O'Connor is set to make his 100th appearance for Ulster as captains a much-changed side from that which recorded a bonus-point victory against Harlequins at Twickenham Stoop last Friday.
In the back three, Rob Lyttle makes his return, this time to the full-back position. He will be joined by Craig Gilroy and Angus Kernohan on the right and left wings.
Matt Faddes makes a positional switch to outside centre and will pair up with Angus Curtis in midfield. Bill Johnston will make his fourth start of the season at fly-half, and David Shanahan gets the starting berth at scrum-half.
In the pack, Andrew Warwick, Adam McBurney and Tom O’Toole make up the starting front row. In the second row, Alan O’Connor will be joined by his brother David, who will be making his first start for Ulster.
Matthew Rea and Nick Timoney have been selected to start on the flanks, with Greg Jones completing the base of the scrum.
Ulster: Rob Lyttle, Craig Gilroy, Matt Faddes, Angus Curtis, Angus Kernohan, Bill Johnston, David Shanahan, Andrew Warwick, Adam McBurney, Tom O'Toole, David O’Connor, Alan O’Connor, Matthew Rea, Nick Timoney, Greg Jones.
Replacements: John Andrew, Kyle McCall, Ross Kane, Jack Regan, Azur Allison, Jonny Stewart, Stewart Moore, Ethan McIlroy.
