Garry Ringrose's second hat-trick of the European season helped Leinster claim a 50-21 victory over Northampton in their Heineken Champions Cup clash at the Aviva Stadium.
Leo Cullen's men provided plenty of entertainment as they booked their quarter-final place with two rounds still remaining.
Adding to last week's 43-16 win at Franklin's Gardens, they are now 10 points clear and guaranteed to finish top of Pool One.
A Ringrose brace inside the opening five minutes set the hosts on their way to a 35th-minute bonus point.
Tadhg Furlong and Dave Kearney also touched down, with the twin threats of man-of-the-match Jordan Larmour and James Lowe consistently posing problems for Saints.
Dan Biggar converted his own try, while Ollie Sleightholme and Ahsee Tuala also crossed the line but Northampton fell short of their bonus point aim.
Further scores from Lowe, Ringrose and Caelan Doris, with Ross Byrne and Ciaran Frawley kicking 15 points between them, steered Leinster to a half-century of points.
The early momentum was seized by Leinster thanks to Ringrose's opener from his charge-down of an Andy Symons kick, with a classy conversion fired over by Byrne.
A crisp midfield move off a lineout then saw Lowe expose a gap, with the help of Byrne, and the winger got his hands free to send Ringrose in under the posts. Byrne converted and tagged on a 10th-minute penalty for a 17-0 advantage.
Biggar provided the spark for Northampton with a sprightly break and then his quickly-taken penalty and neat link with Symons saw the Welsh ace squeeze in under the posts.
However, those seven points were cancelled out when Furlong crashed over from a lineout maul, on the back of Tuala's yellow for pulling back Lowe.
The visitors suffered a second sin-binning with skipper Wood adjudged to have infringed at a ruck near his own line.
The 13 men secured a hard-earned turnover soon after but Doris and Rhys Ruddock ripped the ball back in a tackle to set the wheels in motion for the bonus point score.
Byrne attacked the blindside and Ringrose's well-timed pass sent Kearney cutting in past Sleightholme from the right wing, pocketing Leinster's third bonus of the campaign.
However, Saints hit back before the interval with a well-taken Sleightholme try originating from a Lewis Ludlam interception in his own 22.
Lowe got on the scoresheet inside two minutes of the restart, dotting down from an excellent Byrne grubber, and Ringrose followed up with his third of the night, reacting quickest to loose possession from Taqele Naiyaravoro's attempted rip.
European debutant Frawley, who came on at fly-half, knocked over the conversion to make it 43-14.
There were a couple of near misses from Henshaw and Kearney, who had a try ruled out for an earlier offside, before Northampton enjoyed a purple patch when Samoan full-back Tuala burst clean through from a midfield ruck for a 57th-minute try, raising their hopes of grabbing a bonus point.
However, a similar effort earned number eight Doris his first European score for Leinster, which Frawley converted to wrap up a comprehensive win for the home side.
Elsewhere, Benetton came from behind to edge out Lyon 25-22 and record their first Champions Cup victory of the campaign.
The Guinness Pro14 side reversed last weekend's 28-0 thrashing at Lyon as Ian Keatley's two second-half penalties helped them over the line.
Wingers Leonardo Sarto and Monty Ioane both scored early tries for the hosts, but converted scores for Liam Gill and Rudi Wulf put Lyon 14-12 ahead at half-time.
Former Munster and Ireland player Keatley then kept Benetton in touch, before Pierre-Louis Barassi's try gave the French Top 14 leaders hope - but a late converted try from Marco Lazzaroni saw the Italians through to a first Champions Cup win since 2015.