Ireland will name their team to face Argentina at lunchtime today with a number of frontline players due for reinstatement.
Joe Schmidt brought a largely second string selection to Chicago for what turned out to be a comprehensive 54-7 win over Italy.
Not counting Conor Murray, who continues his recovery from a bulging disc in his neck, Schmidt left 681 caps worth of experience at home with an eye on the upcoming games against Los Pumas on Saturday (6.30pm) and New Zealand on 17 November.
Today’s selection will give a glimpse into the head coach’s thinking with a number of fit players operating close to peak levels, all eager to push ahead of their rivals with the World Cup less than 12 months away.
Full-back Rob Kearney is not expected to be risked having injured his shoulder during Leinster’s win in Treviso two weeks ago.
That means a call between a fit Kearney or Jordan Larmour, who scored a hat-trick against Italy, can be kicked down the road.
The 21-year-old Leinster back is in pole position to start in the absence of his 86-cap team-mate.
Jacob Stockdale was replaced after an hour against Italy with Andrew Conway playing the full game.
The Ulster wing helped himself to two tries in last year’s 28-19 win over Saturday's opponents and the Six Nations top try-scorer would have no qualms about going three weeks in a row if necessary.
Keith Earls, the Irish players' player of the year, is likely to come in on the right wing to earn his 71st cap.
Leinster duo Robbie Henshaw and Garry Ringrose are favourites for the centre berths, while Kieran Marmion is likely to find himself inside fly-half Johnny Sexton.
In the front row, Schmidt is unlikely to stray from the favoured Six Nations combo of Cian Healy, Rory Best and Tadhg Furlong.
However, the New Zealander faces a four-into-two conundrum in the second row with Devin Toner, James Ryan, Tadhg Beirne and Iain Henderson all fit and raring to go.
The back row is equalling intriguing with Peter O’Mahony, Sean O’Brien, CJ Stander the probable starters.
Such is the competition for places, however, that if any of Josh van Flier, Jordi Murphy, Jack Conan, Rhys Ruddock or Dan Leavy get the nod, no one would be totally surprised.
Schmidt is due to announce his 23-man squad at a press conference at Carton House at 1.45pm, with Argentina's team also to be revealed today.
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Follow Ireland v Argentina via our liveblog on RTÉ.ie/sport and the News Now app, watch live on RTÉ2 and the RTÉ Player or listen to live commentary on RTÉ Radio 1 this Saturday (kick-off 6.30pm)