Scotland full-back Stuart Hogg has been ruled out of the November internationals as he is set to undergo surgery on his ankle.
The 26-year-old sustained the injury in Glasgow's win over Munster earlier this month but carried on playing until the closing stages of the match.
He travelled to South Africa but did not feature in Glasgow's win over the Cheetahs and was sent back to Scotland for surgery.
"I'm gutted to be missing some important games for Glasgow Warriors and Scotland over the next few months," Hogg, capped 62 times by Scotland, said in a statement.
"My focus just now is working hard and getting fit, so I can play my part in what is a long season.
"I'd like to thank the medical staff at Glasgow Warriors and BMI Ross Hall Hospital for all their care and support."
Warriors confirmed Hogg is set to spend around 10-12 weeks on the sidelines.
Scotland face Wales in Cardiff on 3 November before taking on Fiji, South Africa and Argentina at Murrayfield.