Kingspan Stadium in Belfast will host an international fixture between the Barbarians and Fiji on Friday 11 November.
This match will form part of the Barbarians' Autumn Tour, which will also see them play against South Africa at Wembley six days earlier.
The Barbarians first travelled to Ireland in 1957, where they played an Ulster Invitation XV in Belfast, and this will be their first visit back to the city since.
Robbie Deans and Will Greenwood will coach the squad for the Autumn series.
The Fiji squad is also likely to contain a number of high profile names, including the likes of former Ulster favourite Timoci Nagusa and Super Rugby sensation Nemani Nadolo.