Ulster head coach Neil Doak has made 12 changes to the side that drew with Munster for tomorrow's Guinness Pro12 match against Glasgow Warriors at Scotstoun (kick-off 3pm).
With a total of six players having picked up injuries last weekend and with the province already guaranteed a play-off place - although still hoping for a win to book a home semi-final - only Franco van der Merwe, Louis Ludik and Chris Henry are retained from the side that faced Munster, with Ireland U20 centre, Sam Arnold, picked for his first start for the province.
Doak has selected a strong bench with internationals Rory Best, Tommy Bowe, Ruan Pienaar, Paddy Jackson, Roger Wilson and Iain Henderson all named among the replacements.
Andrew Warwick comes in at loosehead for his first game since January with Rob Herring at hooker. Emerging Ireland player Ricky Lutton starts his first game of the season at tight-head after a number of injuries.
Lewis Stevenson starts in the second row alongside Van der Merwe, with Robbie Diack starting at No 8, Clive Ross at blindside and Chris Henry captaining from openside.
Scrum-half is Paul Marshall while Ian Humphreys is selected at outhalf.
Stuart McCloskey plays inside-centre, with academy player Sam Arnold starting his first game for Ulster at outside-centre.
Michael Allen, who will play for Edinburgh next season, is on the left wing, with Rory Scholes named on the right and Louis Ludik continuing at full-back.
Ulster: L Ludik; R Scholes, S Arnold, S McCloskey, M Allen, I Humphreys, P Marshall; A Warwick, R Herring, R Lutton, L Stevenson, F van der Merwe, C Ross, C Henry (C), R Diack;
Replacements: R Best, K McCall, B Ross, I Henderson, R Wilson, R Pienaar, P Jackson, T Bowe.
Ian Ketley will win his 100th cap for Munster against Newport-Gwent Dragons at Irish Independent Park tomorrow afternoon (3pm), while Paul O'Connell will line out in Cork for the first time this season.
Head coach Anthony Foley makes five changes to the team that drew with Ulster due to a number of injury concerns.
Tommy O'Donnell sustained a torn hamstring in Saturday's game against Ulster and is expected to be sidelined for approximately six to eight weeks.
Simon Zebo is also ruled out after failing to recover fully from back spasms, however, the winger is expected to make a return to full training next week after further rest.
Duncan Casey and Peter O'Mahony were late withdrawals from this week's squad preparations with the hooker reporting mild back pain and the squad captain picking up a knock in training yesterday. Both players are expected to take a full part in next week's programme.
Denis Hurley is named as captain for the sixth time this season.
John Ryan and BJ Botha come into the front row on either side of Eusebio Guinazu and with Donnacha Ryan making the switch to 6 this weekend, Billy Holland returns to the starting line-up alongside Paul O'Connell in the second row.
Ryan is joined in the back row by Paddy Butler at 7 and last weekend's man-of-the-match CJ Stander, who continues at number 8.
Conor Murray and Ian Keatley – who wins his 100th Munster cap – remain at half back, as do captain Hurley and Andrew Smith in the centre, while the only change in the backline sees Ronan O'Mahony join the back three alongside Keith Earls and Felix Jones.
Munster: Felix Jones; Keith Earls, Andrew Smith, Denis Hurley – capt., Ronan O'Mahony; Ian Keatley, Conor Murray; John Ryan, Eusebio Guinazu, BJ Botha; Billy Holland, Paul O'Connell; Donnacha Ryan, Paddy Butler, CJ Stander.
Replacements: Niall Scannell, Dave Kilcoyne, Stephen Archer, Sean Dougall, Jack O'Donoghue, Duncan Williams, JJ Hanrahan, Andrew Conway.
Leinster have made three changes for their visit to Edinburgh on Saturday (kick-off 3pm).
Noel Reid, Colm O'Shea and Isaac Boss replace Ben Te’o, Jimmy Gopperth and Eoin Reddan from the side that beat Treviso.
Clontarf 24-year-old O'Shea makes his first appearance of the season at outside-centre, while Leinster Academy winger Cian Kelleher could make his senior debut if introduced from the bench.
Both players were involved in the Ulster Bank League final last weekend when Kelleher's Lansdowne side defeated the reigning champions Clontarf. On Thursday evening Kelleher was awarded the Ulster Bank League Rising Star Award for his performances in the league this season.
The pack is the same unit that won last time out with Jack McGrath, Richardt Strauss and Mike Ross in the front row, and Devin Toner and Mike McCarthy in the engine room.
In the back row, Jordi Murphy starts at blindside, Sean O'Brien is at openside flanker and captain Jamie Heaslip number eight.
Rob Kearney is again selected at full-back with brother Dave on the left wing and Zane Kirchner on the right wing.
It's a new centre partnership for the trip to Edinburgh with Reid at inside and O'Shea at outside. As a result Ian Madigan switches to outhalf with Isaac Boss the final change as he starts at scrumhalf.
Tomorrow will be Jimmy Gopperth's last involvement in a Leinster jersey before he moves to Wasps in the summer and should he make an appearance from the bench it will be his 59th cap.
Leinster: R Kearney; Z Kirchner, C O'Shea, N Reid, D Kearney; I Madigan, I Boss; J McGrath, R Strauss, M Ross; D Toner, M McCarthy; J Murphy, S O'Brien, J Heaslip (capt).
Replacements: A Dundon, M Bent, T Furlong, T Denton, J Conan, L McGrath, J Gopperth, C Kelleher.
Pat Lam has made three personnel changes to his Connacht side ahead of their game at home to league leaders Ospreys on Saturday at 3pm.
Scrum-half Kieran Marmion starts in a backline that also sees Connacht centurion and record try scorer Fionn Carr named on the right wing.
Up front, Galway man Andrew Browne is promoted from the bench to join Aly Muldowney in the second row.
John Muldoon, who has started all 22 Pro12 fixtures this season, will once again captain the side from a back row with Eoghan Masterson and Eoin McKeon.
The most notable inclusion on the bench is Connacht's most capped player of all time, Michael Swift, who has worked his way back from injury to take his place amongst the replacements for what could be his last home game before he retires. The 37-year-old, who has played 263 times for the province, is also joined on the bench by Miah Nikora and Shane O'Leary.
Commenting on game, Lam said: "We all know the enormity of this game. Since pre-season, we have set our sights on a top six finish and to be going into round 22 with our ultimate goal still a possibility is very exciting. Its uncharted waters for Connacht Rugby to have so much to play for at this stage of the season and we're really relishing it.
“Come 5pm tomorrow, we will know our fate. We have no control over other results so all we can do is focus on winning at the Sportsground in front of our supporters to give ourselves the best possible chance of qualification and to finish the season on a massive high."
Connacht: Tiernan O'Halloran, Fionn Carr, Robbie Henshaw, Bundee Aki, Matt Healy, Jack Carty, Kieran Marmion, Denis Buckley, Tom McCartney, Rodney Ah You, Andrew Browne, Aly Muldowney, John Muldoon (captain), Eoghan Masterson, Eoin McKeon.
Replacements: Dave Heffernan, JP Cooney, Finlay Bealham, Michael Swift, George Naoupu, John Cooney, Miah Nikora.