Munster prop James Cronin has been ruled out of Ireland's upcoming international fixtures due to injury.
Cronin picked up an ankle injury playing in Munster's 14-3 victory over Saracens at the weekend.
The Cork man has been ruled out of action for at least six weeks and as a result will miss Ireland's fixtures with South Africa, Georgia and Australia.
Cronin will also be a doubt for Munster's upcoming back-to-back Champions Cup encounters with Clermont Auvergne in December.
Meanwhile, Leinster centre Gordon D'Arcy is nursing a groin injury, his team-mate Rob Kearney is still suffering from back spasms and prop Mike Ross is recovering from a niggling groin injury.
Ulster duo Stuart Olding and Tommy Bowe are currently being worked through return-to-play protocols by the Ireland medical team.