Connacht coach Eric Elwood has made two changes to the side that lost to Harlequinns last weekend for this weekend's Challenge Cup meeting with the same side.
Ronan Loughney replaces the injured Brett Wilkinson in the front row, and Darragh Fanning starts on the wing.
Brian Tuohy has been named on the bench.
Connacht team to play Harlequins: Gavin Duffy, Darragh Fanning, Ian Keatley, Keith Matthews, Fionn Carr, Miah Nikora, Frank Murphy, Ronan Loughney, Sean Cronin, Jamie Hagan, Michael Swift, Michael McCarthy, Andrew Browne, Johnny O’Connor, John Muldoon
