Connacht went down 20-9 to Harlequins in the Amlin Challenge Cup Pool One on Sunday at The Stoop.
Tom Guest, who switched to number eight in the absent of the unwell Nick Easter, gave Quins an ideal start when he sliced through from 35 metres, and then made a key contribution to a second try for the team 10 minutes into the second half when he made a break before playing a long ball out for Mike Brown to supply the finish.
Miah Nikora kicked all of Connacht's points, whick Nick Evans booted two penalties and two conversions for Quins.