Felipe Contepomi captains the Leinster side in the absence of Brian O'Driscoll against the Ospreys at Lansdowne Road on Saturday, kick-off at 7.35pm.
Kieran Lewis takes his place and he will be partnered by Gordon D'Arcy at centre.
Bernard Jackman has been named in a strong front row alongside Ronan McCormack and Will Green, while Adam Byrnes partners Malcolm O'Kelly in the second row.
Eric Miller is set to play his final home game for Leinster before his impending retirement after being named in an aggressive backrow alongside Keith Gleeson and Jamie Heaslip.
LEINSTER XV (v Ospreys): G Dempsey, S Horgan, K Lewis, G D'Arcy, D Hickie, F Contepomi, G Easterby, R McCormack, B Jackman, W Green, A Byrnes, M O'Kelly, E Miller, K Gleeson, J Heaslip.
