Watch Saturday's three Six Nations matches live on RTÉ TWO, starting at 1.00pm.
Carlos Nieto has been ruled out of action for more than a month after damaging knee ligaments in Italy's RBS 6 Nations Championship draw in Wales.
The Viadana forward was replaced half-an-hour into Saturday's 18-18 draw at the Millennium Stadium, the Azzurri's first point away from home since joining the competition in 2000.
Head coach Pierre Berbizier has already called up Parma's Fabio Staibano as a replacement for this weekend's final game against Scotland.