Joe Cokanasiga will add firepower to England's back line after being picked on the left wing for Thursday's World Cup clash with the USA at Kobe Misaki Stadium.
Cokanasiga replaces Jonny May in one of 10 changes to the starting XV that launched the Pool C campaign with a 35-3 victory over Tonga in Sapporo.
The giant Fijian-born 21-year-old has been struggling with a knee injury but has been passed fit for the second match of England's four-day turnaround.
Cokanasiga's presence makes up for Manu Tuilagi's absence after the Leicester wrecking ball is rested in the wake of laying waste to Tonga with a devastating two-try salvo.
Captain Owen Farrell drops to the bench so George Ford, who leads the team, continues at fly-half inside a new-look centre combination of Piers Francis and Jonathan Joseph.
Ruaridh McConnochie wins his second cap on the right wing with Elliot Daly continuing at full-back and Willi Heinz getting the nod ahead of Ben Youngs at scrum-half.
There are three survivors from the pack that started against Tonga in prop Joe Marler, flanker Tom Curry and number eight Billy Vunipola.
Vunipola started throughout the warm-up series and continues his run of games after a frustrating spell of injury that saw him suffer three broken arms in a year.
Henry Slade is absent despite making his comeback against Tonga after three months out with a knee injury incurred during last season's Gallagher Premiership final.
Slade came on at full-back at the Sapporo Dome and hurt the same knee that resulted in his summer on the sidelines but was able to finish the match after receiving treatment.
Openside flanker Sam Underhill drops out of the squad completely and there is a return for back row Mark Wilson on the bench following his struggle with a knee injury.
England: Elliot Daly, Ruaridh McConnochie, Jonathan Joseph, Piers Francis, Joe Cokanasiga, George Ford, Willi Heinz, Billy Vunipola, Lewis Ludlam, Tom Curry, George Kruis, Joe Launchbury, Dan Cole, Luke Cowan-Dickie, Joe Marler
Replacements: Jack Singleton, Ellis Genge, Kyle Sinckler, Courtney Lawes, Mark Wilson, Ben Youngs, Owen Farrell, Anthony Watson